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Efficacy and Safety of Prucalopride in Patients with Chronic Noncancer Pain Suffering from Opioid-Induced Constipation

机译：普鲁卡必利对阿片类药物引起的慢性非癌性疼痛患者的疗效和安全性

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BackgroundOpioid-induced constipation (OIC) has negative effects on quality of life (QOL). Prucalopride is a new, selective 5-HT4 agonist and enterokinetic with strong clinical data in chronic constipation. This study investigated the efficacy, safety, and tolerability of prucalopride in patients with noncancer pain and OIC.

机译：背景阿片类药物引起的便秘（OIC）对生活质量（QOL）具有负面影响。普鲁卡必利是一种新型的选择性5-HT4激动剂和肠代谢药，在慢性便秘中具有强大的临床数据。这项研究调查了普卡洛必利在非癌性疼痛和OIC患者中的疗效，安全性和耐受性。

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期刊名称 Springer Open Choice
作者
Cornelius E. J. Sloots; An Rykx; Marina Cools; Rene Kerstens; Martine De Pauw;
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作者单位

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年(卷),期 -1(55),10
年度 -1
页码 2912–2921
总页数 10
原文格式 PDF
正文语种
中图分类外科学;
关键词
Opioid-induced bowel dysfunction Prucalopride Safety Efficacy Constipation;

机译：阿片类药物引起的肠功能障碍;普考氯普利;安全性;功效;便秘;

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专利

1. Efficacy and safety of prucalopride in patients with chronic noncancer pain suffering from opioid-induced constipation. [J] . Sloots CE, Rykx A, Cools M, Digestive Diseases and Sciences . 2010,第10期

机译：普鲁卡必利对阿片类药物致便秘的慢性非癌性疼痛患者的疗效和安全性。
2. Efficacy and Safety of Prucalopride in Patients with Chronic Noncancer Pain Suffering from Opioid-Induced Constipation [J] . Cornelius E. J. Sloots, An Rykx, Marina Cools, Digestive Diseases and Sciences . 2010,第10期

机译：普鲁卡必利对阿片类药物引起的慢性非癌性疼痛患者的疗效和安全性
3. Efficacy and safety of linaclotide for opioid-induced constipation in patients with chronic noncancer pain syndromes from a phase 2 randomized study [J] . Pain. . 2020,第5期

机译：三相随机研究中慢性非癌症疼痛综合征患者阿片类药物诱导的患者的疗效和安全性
4. Study of Efficacy and Safety of Willow Bark Extract (Assalix) in Treatment of Chronic Low Back Pain in Patients of Different Age with Osteochondrosis [C] . V.V. Povoroznyuk, T.A. Karasevskaya International Pain Clinic Congress . 2008

机译：柳树皮提取物（Assalix）治疗不同年龄患者慢性低腰疼痛的疗效和安全性研究
5. Relationship between Skepticism and Nursing Experiences when Treating Chronic Noncancer Pain Patients [D] . Jabour, Emily. 2020

机译：治疗慢性非癌症疼痛患者怀疑与护理经验的关系
6. Efficacy and Safety of Methylnaltrexone for Opioid-Induced Constipation in Patients With Chronic Noncancer Pain [O] . Eugene R. Viscusi, Andrew C. Barrett, Craig Paterson, -1

机译：甲基纳曲酮对阿片类药物引起的慢性非癌性疼痛患者的疗效和安全性
7. Efficacy and Safety of Prucalopride in Patients with Chronic Noncancer Pain Suffering from Opioid-Induced Constipation [O] . Cornelius E. J. Sloots, An Rykx, Marina Cools, 2010

机译：普鲁卡必利对阿片类药物引起的慢性非癌性疼痛患者的疗效和安全性

Efficacy and Safety of Prucalopride in Patients with Chronic Noncancer Pain Suffering from Opioid-Induced Constipation

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