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A Comparison of Pharmacokinetic and Pharmacodynamic Properties Between Faster-Acting Insulin Aspart and Insulin Aspart in Elderly Subjects with Type 1 Diabetes Mellitus

机译：速效天冬胰岛素和天冬氨酸胰岛素在1型糖尿病老年人中药代动力学和药效学性质的比较

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BackgroundDue to population aging, an increasing number of elderly patients with diabetes use insulin. It is therefore important to investigate the characteristics of new insulins in this population. Faster-acting insulin aspart (faster aspart) is insulin aspart (IAsp) in a new formulation with faster absorption. This study investigated the pharmacological properties of faster aspart in elderly subjects with type 1 diabetes mellitus (T1DM).

机译：背景技术由于人口老龄化，越来越多的老年糖尿病患者使用胰岛素。因此，重要的是调查该人群中新胰岛素的特征。作用更快的门冬胰岛素（fast aspart）是一种新的吸收更快的门冬胰岛素（IAsp）。这项研究调查了1型糖尿病（T1DM）老年受试者中更快的天冬氨酸的药理特性。

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期刊名称 Springer Open Choice
作者
Tim Heise; Ulrike Hövelmann; Eric Zijlstra; Kirstine Stender-Petersen; Jacob Bonde Jacobsen; Hanne Haahr;
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作者单位

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年(卷),期 -1(34),1
年度 -1
页码 29–38
总页数 10
原文格式 PDF
正文语种
中图分类外科学;
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专利

1. Pharmacokinetic and Pharmacodynamic Properties of Faster-Acting Insulin Aspart versus Insulin Aspart Across a Clinically Relevant Dose Range in Subjects with Type 1 Diabetes Mellitus [J] . Heise Tim, Stender-Petersen Kirstine, Hoevelmann Ulrike, Clinical pharmacokinetics . 2017,第6期

机译：患有1型糖尿病患者临床相关剂量范围临床相关剂量范围肠道胰岛素Aspart的药代动力学和药效学特性
2. Clinical Pharmacology of Fast-Acting Insulin Aspart Versus Insulin Aspart Measured as Free or Total Insulin Aspart and the Relation to Anti-Insulin Aspart Antibody Levels in Subjects with Type 1 Diabetes Mellitus [J] . Haahr Hanne, Pieber Thomas R., Mathieu Chantal, Clinical pharmacokinetics . 2019,第5期

机译：快速胰岛素Aspart的临床药理学与胰岛素Aspart测量的胰岛素Aspart，以及与1型糖尿病的受试者抗胰岛素Aspart抗体水平的关系
3. Faster-acting insulin aspart provides faster onset and greater early exposure vs insulin aspart in children and adolescents with type 1 diabetes mellitus [J] . Fath Maryam, Danne Thomas, Biester Torben, Journal of Turbulence . 2017,第8期

机译：较快的胰岛素Aspart提供更快的发作和更高的早期暴露对儿童和青少年的胰岛素Aspart，患有1型糖尿病
4. PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES OF INSULIN ASPART FOLLOWING SUBCUTANEOUS AND INTRAMUSCULAR INJECTION IN CATS [C] . Hannah Pipe-Martin, Jon Fletcher, Chen Gilor, Conference of the American^College^of^Veterinary^Internal^Medicine . 2016

机译：胰岛素肌肉内注射后胰岛素Aspart的药物动力学和药代动力学特性
5. Modeling of the insulin pathway in insulin therapy to improve normoglycemic control of patients wtih type 1 diabetes mellitus [D] . Chan, Alice 2011

机译：胰岛素治疗中胰岛素途径的建模以改善1型糖尿病患者的正常血糖控制
6. Pharmacokinetic and Pharmacodynamic Properties of Faster-Acting Insulin Aspart versus Insulin Aspart Across a Clinically Relevant Dose Range in Subjects with Type 1 Diabetes Mellitus [O] . Tim Heise, Kirstine Stender-Petersen, Ulrike Hövelmann, -1

机译：1型糖尿病患者在临床相关剂量范围内速效门冬胰岛素与门冬胰岛素的药代动力学和药效学性质
7. A Comparison of Pharmacokinetic and Pharmacodynamic Properties Between Faster-Acting Insulin Aspart and Insulin Aspart in Elderly Subjects with Type 1 Diabetes Mellitus [O] . 2017

机译：速效天冬胰岛素和天冬氨酸胰岛素在1型糖尿病老年人中药代动力学和药效学性质的比较

A Comparison of Pharmacokinetic and Pharmacodynamic Properties Between Faster-Acting Insulin Aspart and Insulin Aspart in Elderly Subjects with Type 1 Diabetes Mellitus

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