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A Comparison of Drug Transport in Pulmonary Absorption Models: Isolated Perfused rat Lungs Respiratory Epithelial Cell Lines and Primary Cell Culture

机译：肺部吸收模型中药物传输的比较：分离的灌注大鼠肺呼吸道上皮细胞系和原代细胞培养

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摘要

PurposeTo evaluate the ability of human airway epithelial cell layers and a simple rat isolated perfused lung (IPL) model to predict pulmonary drug absorption in rats in vivo.

机译：目的评估人气道上皮细胞层和简单大鼠离体灌注肺（IPL）模型预测大鼠体内肺药物吸收的能力。

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期刊名称 Springer Open Choice
作者
Cynthia Bosquillon; Michaela Madlova; Nilesh Patel; Nicola Clear; Ben Forbes;
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作者单位

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年(卷),期 -1(34),12
年度 -1
页码 2532–2540
总页数 9
原文格式 PDF
正文语种
中图分类外科学 ;
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专利

1. A Comparison of Drug Transport in Pulmonary Absorption Models: Isolated Perfused rat Lungs, Respiratory Epithelial Cell Lines and Primary Cell Culture [J] . Bosquillon Cynthia, Madlova Michaela, Patel Nilesh, Pharmaceutical research . 2017 ,第12期

机译：肺动吸收模型中药物运输的比较：分离灌注大鼠肺，呼吸上皮细胞系和原发性细胞培养
2. Expression and Transport Functionality of FcRn within Rat Alveolar Epithelium: A Study in Primary Cell Culture and in the Isolated Perfused Lung [J] . Masahiro Sakagami, Yadollah Omidi, Lee Campbell, Pharmaceutical Research . 2006 ,第2期

机译：FcRn在大鼠肺泡上皮中的表达和转运功能：在原代细胞培养和离体灌注肺中的研究
3. Expression and transport functionality of FcRn within rat alveolar epithelium: a study in primary cell culture and in the isolated perfused lung. [J] . Sakagami M, Omidi Y, Campbell L, Pharmaceutical research . 2006 ,第2期

机译：FcRn在大鼠肺泡上皮中的表达和运输功能：在原代细胞培养和离体灌注肺中的研究。
4. Comparison of three different epithelial cell-culture models to study drug absorption across biological barriers [C] . H.Franke, C.Gindorf, U.Bock, International symposium on controlled release of bioactive materials;Consumer and diversified products conference . 2000

机译：比较三种不同的上皮细胞培养模型以研究跨生物屏障的药物吸收
5. Pulmonary absorption of fluorophore-labeled polyaspartamides from the airways of the isolated perfused rat lung. [D] . Sun, John Zhuang. 1995

机译：荧光标记的聚天冬酰胺从分离的灌注大鼠肺的气道中的肺吸收。
6. Comparison of a Rat Primary Cell-Based Blood-Brain Barrier Model With Epithelial and Brain Endothelial Cell Lines: Gene Expression and Drug Transport [O] . Szilvia Veszelka, András Tóth, Fruzsina R. Walter, 2018

机译：基于大鼠原代细胞的血脑屏障模型与上皮和脑内皮细胞系的比较：基因表达和药物转运
7. A comparison of drug transport in pulmonary absorption models: isolated perfused rat lungs, respiratory epithelial cell lines and primary cell culture [O] . Bosquillon Cynthia, Madlova Michaela, Patel Nilesh, 2017

机译：肺部吸收模型中药物转运的比较：分离的灌流大鼠肺，呼吸道上皮细胞系和原代细胞培养
8. Respiratory Syncytial Virus Infection of Human Primary Nasal and Bronchial Epithelial Cell Cultures and Bronchoalveolar Macrophages. [R] . Becker, S., Soukup, J., Yankaskas, J. 1992

机译：呼吸道合胞病毒感染人原发性鼻和支气管上皮细胞培养及支气管肺泡巨噬细胞。

A Comparison of Drug Transport in Pulmonary Absorption Models: Isolated Perfused rat Lungs Respiratory Epithelial Cell Lines and Primary Cell Culture

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