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Safety and Plasma Concentrations of a Cyclin-dependent Kinase 9 (CDK9) Inhibitor FIT039 Administered by a Single Adhesive Skin Patch Applied on Normal Skin and Cutaneous Warts

机译：周期蛋白依赖性激酶9（CDK9）抑制剂FIT039的安全性和血浆浓度由适用于正常皮肤和皮肤疣的单一粘性皮肤贴剂管理

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BackgroundCutaneous warts are caused by human papilloma virus (HPV) infection. FIT039, a specific inhibitor of CDK9, suppresses the proliferation of DNA viruses in vitro.

机译：背景疣是由人乳头瘤病毒（HPV）感染引起的。 FIT039是CDK9的特异性抑制剂，可在体外抑制DNA病毒的增殖。

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期刊名称 Springer Open Choice
作者
Eriko Sumi; Takashi Nomura; Ryuta Asada; Ryuji Uozumi; Harue Tada; Yoko Amino; Teruo Sawada; Atsushi Yonezawa; Masatoshi Hagiwara; Kenji Kabashima;
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作者单位

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年(卷),期 -1(39),1
年度 -1
页码 55–61
总页数 7
原文格式 PDF
正文语种
中图分类外科学;
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专利

1. Safety and Plasma Concentrations of a Cyclin-dependent Kinase 9 (CDK9) Inhibitor, FIT039, Administered by a Single Adhesive Skin Patch Applied on Normal Skin and Cutaneous Warts [J] . Sumi Eriko, Nomura Takashi, Asada Ryuta, Clinical drug investigation . 2019,第1期

机译：通过在正常皮肤和皮肤疣上施加的单一粘合性皮肤贴剂给药的安全性和血浆浓度为细胞周期蛋白依赖性激酶9（CDK9）抑制剂FIT039
2. High prevalence of cutaneous warts in elementary school children and the ubiquitous presence of wart-associated human papillomavirus on clinically normal skin [J] . de Koning M. N. C., Quint K. D., Bruggink S. C., British Journal of Dermatology . 2015,第1期

机译：小学儿童皮肤疣的患病率高，临床上正常皮肤上普遍存在与疣相关的人乳头瘤病毒
3. Safety, tolerability, pharmacokinetics and pharmacodynamics of the oral cyclin-dependent kinase inhibitor AZD5438 when administered at intermittent and continuous dosing schedules in patients with advanced solid tumours. [J] . Boss DS, Schwartz GK, Middleton MR, Annals of oncology: official journal of the European Society for Medical Oncology . 2010,第4期

机译：在晚期实体瘤患者中以间歇和连续给药方案给药时，口服细胞周期蛋白依赖性激酶抑制剂AZD5438的安全性，耐受性，药代动力学和药效学。
4. The Effectiveness of an Adhesively Bonded Composite Patch Repair as Applied to a Transport Aircraft Lower Wing Skin [C] . John J. Ruschau, Jack E. Coate International SAMPE symposium and exhibition . 1996

机译：应用于运输机下机翼蒙皮的胶粘复合修补程序的有效性
5. Phase 1 safety pharmacokinetic and pharmacodynamic study of the cyclin-dependent kinase inhibitor dinaciclib administered every three weeks in patients with advanced malignancies [O] . Monica M Mita, Alain C Mita, Jennifer L Moseley, 2017

机译：晚期恶性肿瘤患者每三周服用细胞周期蛋白依赖性激酶抑制剂dinaciclib的1期安全性药代动力学和药效学研究
6. Safety and Plasma Concentrations of a Cyclin-dependent Kinase 9 (CDK9) Inhibitor, FIT039, Administered by a Single Adhesive Skin Patch Applied on Normal Skin and Cutaneous Warts [O] . Eriko Sumi, Takashi Nomura, Ryuta Asada, 2018

机译：通过在正常皮肤和皮肤疣上施加的单一粘合性皮肤贴剂给药的安全性和血浆浓度为细胞周期蛋白依赖性激酶9（CDK9）抑制剂FIT039

Safety and Plasma Concentrations of a Cyclin-dependent Kinase 9 (CDK9) Inhibitor FIT039 Administered by a Single Adhesive Skin Patch Applied on Normal Skin and Cutaneous Warts

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