Genes for the tumor necrosis factors alpha and beta are linked to the human major histocompatibility complex.

机译：肿瘤坏死因子α和β的基因与人类主要组织相容性复合体相关。

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摘要

The human major histocompatibility complex (MHC) includes the closely linked genes for the tumor necrosis factors alpha and beta. Their location is within the chromosomal segment between HLA-DR and HLA-A or centromeric of HLA-DP. This assignment is based on Southern blot analysis of a number of different MHC deletion mutants and is corroborated by chromosome in situ hybridization.

机译：人类主要组织相容性复合体（MHC）包括与肿瘤坏死因子α和β密切相关的基因。它们的位置在HLA-DR和HLA-A或HLA-DP着丝粒之间的染色体片段内。该分配基于许多不同的MHC缺失突变体的Southern印迹分析，并通过染色体原位杂交得到证实。

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期刊名称 Proceedings of the National Academy of Sciences of the United States of America
作者
T Spies; C C Morton; S A Nedospasov; W Fiers; D Pious; J L Strominger;
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年(卷),期 2013(83),22
年度 2013
页码 8699–8702
总页数 4
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1. Tumor necrosis factor alpha, interleukin-1 beta, interleukin-6 and major histocompatibility complex molecules in the normal brain and after peripheral immune challenge. [J] . Tonelli LH, Postolache TT Neurological Research: An Interdisciplinary Quarterly Journal . 2005,第7期

机译：正常脑和外周免疫攻击后的肿瘤坏死因子α，白介素-1β，白介素-6和主要组织相容性复合物分子。
2. Tumor Necrosis Factor Alpha-Induced Hypoxia-Inducible Factor 1α–β-Catenin Axis Regulates Major Histocompatibility Complex Class I Gene Activation through Chromatin Remodeling [J] . Sadashib Ghosh, Arkoprovo Paul, Ellora Sen Molecular and Cellular Biology . 2013,第14期

机译：肿瘤坏死因子α诱导的缺氧诱导因子1α–β-连环蛋白轴通过染色质重塑调节主要组织相容性复杂的I类基因激活。
3. Establishment and evaluation of a transgenic mouse model of arthritis induced by overexpressing human tumor necrosis factor alpha Establishment and evaluation of a transgenic mouse model of arthritis induced by overexpressing human tumor necrosis factor alpha Establishment and evaluation of a transgenic mouse model of arthritis induced by overexpressing human tumor necrosis factor alpha [J] . Huanhuan Jia, Yu Zhang, Ren Huang, Biology Open . 2016,第4期

机译：过表达人类肿瘤坏死因子α诱导的关节炎的转基因小鼠模型的建立和评估建立过评估人类肿瘤坏死因子α诱导的关节炎的转基因小鼠模型的建立和评估肿瘤坏死因子α
4. Effect of CV6209, A platelet-activating factor antagonist, on shiga toxin-induced tumor necrosis factor-alpha expression in human monocytic cells [C] . Hui-Min Zhang, Tatsuo Yamamoto 7th China-Japan International Congress of Microbiology Shanghai Symposium-2000 4-6 August 2000 Shanghai . 2000

机译：血小板活化因子拮抗剂CV6209对芝加毒素诱导的人单核细胞中肿瘤坏死因子-α表达的影响
5. Factors shed by breast tumor cells, tumor necrosis factor alpha converting enzyme activities, and the generation of pro-tumor macrophages. [D] . Rego, Stephen Lee. 2013

机译：乳腺肿瘤细胞脱落的因子，肿瘤坏死因子α转换酶的活性以及促肿瘤巨噬细胞的产生。
6. Linkage map of the human major histocompatibility complex including the tumor necrosis factor genes. [O] . M C Carroll, P Katzman, E M Alicot, 1987

机译：人类主要组织相容性复合体的连锁图谱包括肿瘤坏死因子基因。
7. Genes for the tumor necrosis factors alpha and beta are linked to the human major histocompatibility complex. [O] . Spies, T, Morton, C C, Nedospasov, S A, 1986

机译：肿瘤坏死因子α和β的基因与人类主要组织相容性复合体相关。
8. Effect of Interleukin-1beta and Tumor Necrosis Factor-alpha on Gene Expression in Human Endothelial Cells. [R] . Zhao, B., Stavchansky, S. A., Bowden, R. A., 2003

机译：白细胞介素-1β和肿瘤坏死因子-α对人内皮细胞基因表达的影响。

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Genes for the tumor necrosis factors alpha and beta are linked to the human major histocompatibility complex.

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