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Molecular Signatures of Prostate Stem Cells Reveal Novel Signaling Pathways and Provide Insights into Prostate Cancer

机译：前列腺干细胞的分子特征揭示了新的信号通路并提供了对前列腺癌的见解

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BackgroundThe global gene expression profiles of adult and fetal murine prostate stem cells were determined to define common and unique regulators whose misexpression might play a role in the development of prostate cancer.

机译：背景技术确定了成年和胎儿鼠前列腺干细胞的全球基因表达谱，以定义共同的和独特的调节剂，其错误表达可能在前列腺癌的发展中起作用。

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期刊名称 PLoS Clinical Trials
作者
Roy Blum; Rashmi Gupta; Patricia E. Burger; Christopher S. Ontiveros; Sarah N. Salm; Xiaozhong Xiong; Alexander Kamb; Holger Wesche; Lisa Marshall; Gene Cutler; Xiangyun Wang; Jiri Zavadil; David Moscatelli; E. Lynette Wilson;
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年(卷),期 2009(4),5
年度 2009
页码 e5722
总页数 14
原文格式 PDF
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专利

1. Autocrine HGF/c‐MET signaling in prostate cancer stem‐like cells/cancer‐initiating cells. Prostate adenocarcinoma tissue was stained by anti‐SOX2 and anti‐HGF antibodies. HGF is expressed in prostate adenocarcinoma tissue [J] . Asanuma Hiroko, Hirohashi Yoshihiko, Inoue Ryuta, Cancer science. . 2013,第4期

机译：前列腺癌干样细胞/癌起始细胞中的自分泌HGF / c-MET信号传导。前列腺腺癌组织用抗-SOX2和抗-HGF抗体染色。 HGF在前列腺腺癌组织中表达
2. Cuprous oxide nanoparticles inhibit prostate cancer by attenuating the stemness of cancer cells via inhibition of the Wnt signaling pathway [J] . Ye Wang, Qi-Wei Yang, Qing Yang, International Journal of Nanomedicine . 2017,第Supplementa1期

机译：氧化亚铜纳米粒子通过抑制Wnt信号传导途径减弱癌细胞的干性来抑制前列腺癌
3. PHF21B overexpression promotes cancer stem cell-like traits in prostate cancer cells by activating the Wnt/β-catenin signaling pathway [J] . Qiji Li, Liping Ye, Wei Guo, Journal of experimental & clinical cancer research : . 2017,第1期

机译：PHF21B过表达通过激活Wnt /β-catenin信号通路促进前列腺癌细胞中的癌症干细胞样特征
4. MicroRNA expression analysis reveals significant biological pathways in human prostate cancer [C] . Yifei Tang, Chen Jiajia, Cheng Luo, 2011 IEEE International Conference on Systems Biology . 2011

机译：MicroRNA表达分析揭示了人类前列腺癌的重要生物学途径
5. Fibroblast growth factor signaling in prostate stem cells and prostate cancer [D] . Huang, Yanqing. 2015

机译：前列腺干细胞和前列腺癌中的成纤维细胞生长因子信号转导
6. Molecular Signatures of the Primitive Prostate Stem Cell Niche Reveal Novel Mesenchymal-Epithelial Signaling Pathways [O] . Roy Blum, Rashmi Gupta, Patricia E. Burger, 2010

机译：原始前列腺干细胞生态位的分子特征揭示了新型间充质-上皮信号通路。
7. Molecular signatures of prostate stem cells reveal novel signaling pathways and provide insights into prostate cancer [O] . Blum, Roy, Gupta, Rashmi, Burger, Patricia E, 2009

机译：前列腺干细胞的分子标记揭示了新的信号通路，并提供了对前列腺癌的见解
8. Molecular Determinants of Prostate Cancer Progression Across Race- Ethnicity. Project A - The Human 5RD5A2 Gene and Prostate Cancer Progression. Project B - Androgen Receptor (AR) Signaling in Prostate Cancer Progression. Project C - Cellular and Molecular Markers of Prostate Cancer Progression Core - Epidemiology Core [R] . Ross, R. R. , Reichardt, J. , Coetzee, G. A. , 2002

机译：跨越种族的前列腺癌进展的分子决定因素。项目a - 人类5RD5a2基因和前列腺癌进展。项目B - 雄激素受体（aR）在前列腺癌进展中的信号传导。项目C - 前列腺癌进展核心的细胞和分子标记 - 流行病学核心

Molecular Signatures of Prostate Stem Cells Reveal Novel Signaling Pathways and Provide Insights into Prostate Cancer

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