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α23-Sialyltransferase ST3Gal III Modulates Pancreatic Cancer Cell Motility and Adhesion In Vitro and Enhances Its Metastatic Potential In Vivo

机译：α23-唾液酸转移酶ST3Gal III体外调节胰腺癌细胞的运动和粘附并增强其体内转移潜能

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BackgroundCell surface sialylation is emerging as an important feature of cancer cell metastasis. Sialyltransferase expression has been reported to be altered in tumours and may account for the formation of sialylated tumour antigens. We have focused on the influence of alpha-2,3-sialyltransferase ST3Gal III in key steps of the pancreatic tumorigenic process.

机译：背景细胞表面唾液酸化正在成为癌细胞转移的重要特征。据报道，唾液酸转移酶的表达在肿瘤中发生改变，并可能解释了唾液酸化的肿瘤抗原的形成。我们已经集中在胰腺癌发生过程的关键步骤中α-2，3-唾液酸转移酶ST3Gal III的影响。

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期刊名称 PLoS Clinical Trials
作者
Marta Pérez-Garay; Beatriz Arteta; Lluís Pagès; Rafael de Llorens; Carme de Bolòs; Fernando Vidal-Vanaclocha; Rosa Peracaula;
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年(卷),期 2010(5),9
年度 2010
页码 e12524
总页数 11
原文格式 PDF
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专利

1. α2,3-Sialyltransferase ST3Gal III Modulates Pancreatic Cancer Cell Motility and Adhesion In Vitro and Enhances Its Metastatic Potential In Vivo [J] . Marta Pérez-Garay, Beatriz Arteta, Lluís Pagès, PLoS One . 2010,第9期

机译：α2,3-唾液酸转移酶ST3Gal III体外调节胰腺癌细胞的运动和粘附并增强其体内转移潜能
2. ST3Gal III modulates breast cancer cell adhesion and invasion by altering the expression of invasion-related molecules [J] . Cui Hong-Xia, Wang Honglan, Wang Yuchun, Oncology reports . 2016,第6期

机译：ST3Gal III通过改变侵袭相关分子的表达来调节乳腺癌细胞的粘附和侵袭
3. Transgelin increases metastatic potential of colorectal cancer cells in vivo and alters expression of genes involved in cell motility [J] . Hui-min Zhou, Yuan-yuan Fang, Paul M. Weinberger, BMC Cancer . 2016,第1期

机译：Transgelin增加体内大肠癌细胞的转移潜力，并改变参与细胞运动的基因的表达
4. The Human IIIb-mRNA Splice Variant of FGF-receptor-1 Reduces the Transforming Potential of Pancreatic Cancer Cells in vitro and in vivo [C] . M. Thiere, Z. Liu, D. Henne-Bruns, European Society for Surgical Research . 2006

机译：FGF受体-1的人IIIB-mRNA剪接变体降低了体外和体内胰腺癌细胞的转化潜力
5. Umbilical cord blood derived endothelial progenitor cells: Isolation, characterization, and adhesion potential in vitro and in vivo. [D] . Brown, Melissa Ann. 2009

机译：脐带血来源的内皮祖细胞：体外和体内的分离，鉴定和粘附潜力。
6. Human β-galactoside α-23-sialyltransferase (ST3Gal III) attenuated Taxol-induced apoptosis in ovarian cancer cells by downregulating caspase-8 activity [O] . Su Huang, Travis W. Day, Mi-Ran Choi, -1

机译：通过下调Caspase-8活性人β-半乳糖苷α-23-唾液酸转移酶（ST3GAL III）减弱卵巢癌细胞中的紫杉醇诱导的细胞凋亡
7. α2,3-Sialyltransferase ST3Gal III Modulates Pancreatic Cancer Cell Motility and Adhesion In Vitro and Enhances Its Metastatic Potential In Vivo [O] . Pérez Garay, Marta, Arteta, Beatriz, Pagès, Lluís, 2010

机译：α2,3-唾液酸转移酶ST3Gal III体外调节胰腺癌细胞的运动和粘附并增强其体内转移潜能

α23-Sialyltransferase ST3Gal III Modulates Pancreatic Cancer Cell Motility and Adhesion In Vitro and Enhances Its Metastatic Potential In Vivo

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