Abnormalities in gray matter volume in patients with borderline personality disorder and their relation to lifetime depression: A VBM study

摘要

BackgroundStructural imaging studies of borderline personality disorder (BPD) have found regions of reduced cortical volume, but these have varied considerably across studies. Reduced hippocampus and amygdala volume have also been a regular finding in studies using conventional volumetric measurement. How far comorbid major depression, which is common in BPD and can also affect in brain structure, influences the findings is not clear.