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Hypertonic Saline for Brain Relaxation and Intracranial Pressure in Patients Undergoing Neurosurgical Procedures: A Meta-Analysis of Randomized Controlled Trials

机译:高渗盐水对进行神经外科手术的患者的脑部放松和颅内压的影响:随机对照试验的荟萃分析

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摘要

BackgroundA wealth of evidence from randomized controlled trials (RCTs) has indicated that hypertonic saline (HS) is at least as effective as, if not better than, mannitol in the treatment of increased intracranial pressure(ICP). However, there is little known about the effects of HS in patients during neurosurgery. Thus, this meta-analysis was performed to compare the intraoperative effects of HS with mannitol in patients undergoing craniotomy.
机译:背景技术随机对照试验(RCT)的大量证据表明,高渗盐水(HS)在治疗颅内压增高(ICP)方面至少与甘露醇一样有效,甚至比甘露醇好。然而,关于神经外科手术期间HS对患者的影响知之甚少。因此,进行这项荟萃分析,以比较HS和甘露醇对开颅手术患者的术中效果。

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