首页> 美国卫生研究院文献>PLoS Clinical Trials >Polymorphisms in MTHFR, MS and CBS Genes and Homocysteine Levels in a Pakistani Population

【2h】

Polymorphisms in MTHFR, MS and CBS Genes and Homocysteine Levels in a Pakistani Population

机译：巴基斯坦人群中MTHFR，MS和CBS基因的多态性和同型半胱氨酸水平

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

BackgroundHyperhomocysteinemia (>15 µmol/L) is highly prevalent in South Asian populations including Pakistan. In order to investigate the genetic determinants of this condition, we studied 6 polymorphisms in genes of 3 enzymes - methylenetetrahydrofolate reductase (MTHFR; C677T; A1298C), methionine synthase (MS; A2756G), cystathionine-β-synthase (CBS; T833C/844ins68, G919A) involved in homocysteine metabolism and investigated their interactions with nutritional and environmental factors in a Pakistani population.

机译：背景高同型半胱氨酸血症（> 15 µmol / L）在包括巴基斯坦在内的南亚人群中非常普遍。为了研究这种情况的遗传决定因素，我们研究了三种酶的基因中的6个多态性-亚甲基四氢叶酸还原酶（MTHFR; C677T; A1298C），蛋氨酸合酶（MS; A2756G），胱硫醚-β-合酶（CBS; T833C / 844ins68 （G919A）参与同型半胱氨酸代谢，并调查了它们与巴基斯坦人口中营养和环境因素的相互作用。

著录项

期刊名称 PLoS Clinical Trials
作者
Mohsin Yakub; Naushad Moti; Siddiqa Parveen; Bushra Chaudhry; Iqbal Azam; Mohammad Perwaiz Iqbal;
展开▼
作者单位

展开▼
年(卷),期 2009(7),3
年度 2009
页码 e33222
总页数 7
原文格式 PDF
正文语种
中图分类
关键词

相似文献

外文文献
中文文献
专利

1. Polymorphisms in the CBS gene and homocysteine, folate and vitamin B12 levels: association with polymorphisms in the MTHFR and MTRR genes in Brazilian children. [J] . Alessio AC, Siqueira LH, Bydlowski SP, American journal of medical genetics, Part A . 2008 ,第20期

机译：CBS基因多态性与高半胱氨酸，叶酸和维生素B12水平：与巴西儿童MTHFR和MTRR基因多态性相关。
2. Estimation of Homocysteine Level and Methylenetetrahydrofolate Reductase (MTHFR) Gene and Cystathionine B Synthase (CBS) Gene Polymorphisms in Vitiligo Patients [J] . El Tahlawi Samar, Halim Dalia M. Abdel, El Hadidi Heba, Skin pharmacology and physiology . 2020 ,第1期

机译：白癜风水平和亚甲基四氢盐还原酶（MTHFR）基因及胱硫代啶氨酸B合酶（CBS）基因多态性估算白癜风患者的基因多态性
3. Interactions among methylenetetrahydrofolate reductase (MTHFR) and cystathionine ?2-synthase (CBS) polymorphisms - a cross-sectional study: multiple heterozygosis as a risk factor for higher homocysteine levels and vaso-occlusive episodes [J] . F.M. Amaral, A.L. Mir, a-Vilela, Genetics and Molecular Research . 2017 ,第1期

机译：亚甲基四氢叶酸还原酶（MTHFR）和胱硫醚α2-合酶（CBS）多态性之间的相互作用-一项横断面研究：多种杂合酶是高半胱氨酸水平和血管闭塞性发作的危险因素
4. Relationship of homocysteine levels and MTHFR C677T polymorphism with classical vascular risk factors in a general population [C] . Dulin E., Sanchez M.J., Guisasola M.C. International Congress on Coronary Artery Disease . 2009

机译：普通群体古典血管危险因素与MTHFR C677T多态性的关系
5. High degree of genetic polymorphism in apolipoprotein(a) associated with plasma lipoprotein(a) levels in Japanese and Chinese populations [D] . Kikuchi Syuuichi 1994

机译：日本和中国人群中载脂蛋白（a）与血浆脂蛋白（a）水平相关的高度遗传多态性
6. Association of Methylenetetrahydrofolate Reductase (MTHFR 677CT and 1298AC) Polymorphisms and Haplotypes with Silent Brain Infarction and Homocysteine Levels in a Korean Population [O] . In Bo Han, Ok Joon Kim, Jung Yong Ahn, 2010

机译：亚甲基四氢叶酸还原酶（MTHFR 677C T和1298A C）多态性和单倍型与沉默的脑梗死和高半胱氨酸水平在韩国人口中的关联。
7. Polymorphisms in MTHFR, MS and CBS Genes and Homocysteine Levels in a Pakistani Population [O] . Yakub, Mohsin, Moti, Naushad, Parveen, Siddiqa, 2012

机译：巴基斯坦人群中MTHFR，MS和CBS基因的多态性和同型半胱氨酸水平

Polymorphisms in MTHFR, MS and CBS Genes and Homocysteine Levels in a Pakistani Population

摘要

著录项

相似文献

相关主题

期刊订阅