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Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound Healing

机译：Kruppel样因子KLF4在小鼠毛囊干细胞中的表达有助于皮肤伤口愈合。

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摘要

BackgroundKruppel-like factor KLF4 is a transcription factor critical for the establishment of the barrier function of the skin. Its function in stem cell biology has been recently recognized. Previous studies have revealed that hair follicle stem cells contribute to cutaneous wound healing. However, expression of KLF4 in hair follicle stem cells and the importance of such expression in cutaneous wound healing have not been investigated.

机译：背景类似Kruppel的因子KLF4是对建立皮肤屏障功能至关重要的转录因子。近来其在干细胞生物学中的功能得到了认可。先前的研究表明，毛囊干细胞有助于皮肤伤口的愈合。但是，尚未研究毛囊干细胞中KLF4的表达及其在皮肤伤口愈合中的重要性。

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期刊名称 PLoS Clinical Trials
作者
Juan Li; Hai Zheng; Junfeng Wang; Fang Yu; Rebecca J. Morris; Timothy C. Wang; Shiang Huang; Walden Ai;
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年(卷),期 2009(7),6
年度 2009
页码 e39663
总页数 10
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专利

1. Kruppel-Like Factor KLF4 Facilitates Cutaneous Wound Healing by Promoting Fibrocyte Generation from Myeloid-Derived Suppressor Cells [J] . Ou Lingling, Shi Ying, Dong Wenqi, The Journal of investigative dermatology. . 2015 ,第5期

机译：Kruppel样因子KLF4通过促进骨髓来源的抑制细胞生成纤维细胞来促进皮肤伤口愈合
2. Pigment epithelium-derived factor short peptides facilitate full-thickness cutaneous wound healing by promoting epithelial basal cell and hair follicle stem cell proliferation [J] . Tsai Shawn H., Tsao Li-Pen, Chang Shih-Hsin, Experimental and therapeutic medicine . 2017 ,第5aPta2期

机译：颜料上皮衍生的因子短肽通过促进上皮基底细胞和毛囊干细胞增殖来促进全厚的皮肤伤口愈合
3. Photoactivation of ROS Production In Situ Transiently Activates Cell Proliferation in Mouse Skin and in the Hair Follicle Stem Cell Niche Promoting Hair Growth and Wound Healing. [J] . Elisa Carrasco, María I Calvo, Alfonso Blázquez-Castro, The Journal of investigative dermatology. . 2015 ,第11期

机译：ROS产生的光活化原位瞬时激活小鼠皮肤和毛囊干细胞生态位中的细胞增殖，促进毛发生长和伤口愈合。
4. Minocycline enhances the mesenchymal stromal/stem cell pro-healing phenotype in triple antimicrobial-loaded #hydrogels for inoculated cutaneous wound healing [C] . Alberto Daniel Guerra, Warren E Rose, Peiman Hematti, Society for Biomaterials annual meeting and exposition . 2017

机译：米诺环素增强三联抗菌药物＃水凝胶中的间充质基质/干细胞促愈合表型，以接种皮肤伤口愈合
5. Cellular dynamics in the niche of infrequently dividing hair follicle stem cells in the mouse Mus musculus [D] . Zhang, Ying 2010

机译：小鼠小家鼠毛囊干细胞不频繁分裂的生态位中的细胞动力学
6. Pigment epithelium-derived factor short peptides facilitate full-thickness cutaneous wound healing by promoting epithelial basal cell and hair follicle stem cell proliferation [O] . Shawn H. Tsai, Li-Pen Tsao, Shih-Hsin Chang, -1

机译：色素上皮衍生因子短肽通过促进上皮基底细胞和毛囊干细胞增殖促进全层皮肤伤口愈合
7. Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound Healing [O] . Li, Juan, Zheng, Hai, Wang, Junfeng, 2012

机译：Kruppel样因子KLF4在小鼠毛囊干细胞中的表达有助于皮肤伤口愈合。

Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound Healing

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