Optimal Pandemic Influenza Vaccine Allocation Strategies for the Canadian Population

摘要

BackgroundThe world is currently confronting the first influenza pandemic of the 21^st century. Influenza vaccination is an effective preventive measure, but the unique epidemiological features of swine-origin influenza A (H1N1) (pH1N1) introduce uncertainty as to the best strategy for prioritization of vaccine allocation. We sought to determine optimal prioritization of vaccine distribution among different age and risk groups within the Canadian population, to minimize influenza-attributable morbidity and mortality.