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Chitosan Modification of Adenovirus to Modify Transfection Efficiency in Bovine Corneal Epithelial Cells

机译：腺病毒的壳聚糖修饰以修饰牛角膜上皮细胞的转染效率

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摘要

BackgroundThe purpose of this study is to modulate the transfection efficiency of adenovirus (Ad) on the cornea by the covalent attachment of chitosan on adenoviral capsids via a thioether linkage between chitosan modified with 2-iminothiolane and Ad cross-linked with N-[γ-maleimidobutyryloxy]succinimide ester (GMBS).

机译：背景研究的目的是通过将壳聚糖与2-亚氨基硫杂环戊烷修饰的壳聚糖和与N- [γ-马来酰亚胺基丁酰氧基]琥珀酰亚胺酯（GMBS）。

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期刊名称 PLoS Clinical Trials
作者
I-Jong Wang; Min-Chao Jhuang; Yu-Hsin Chen; Lung-Kun Yeh; Chia-Yang Liu; Tai-Horng Young;
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年(卷),期 2010(5),8
年度 2010
页码 e12085
总页数 10
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专利

1. Development of lysine-histidine dendron modified chitosan for improving transfection efficiency in HEK293 cells [J] . Chang K.-L., Higuchi Y., Kawakami S., Journal of Controlled Release: Official Journal of the Controlled Release Society . 2011 ,第2期

机译：赖氨酸-组氨酸树突修饰的壳聚糖的开发，以提高HEK293细胞的转染效率
2. Characterization of the modified chitosan membrane cross-linked with genipin for the cultured corneal epithelial cells [J] . Li Ya-Han, Cheng Ching-Yi, Wang Nan-Kai, Colloids and Surfaces, B. Biointerfaces . 2015 ,第Null期

机译：Genipin交联的改性壳聚糖膜对培养的角膜上皮细胞的表征
3. Expression of claudins -2 and -4 and cingulin is coordinated with the start of stratification and differentiation in corneal epithelial cells: retinoic acid reversibly disrupts epithelial barrier Expression of claudins -2 and -4 and cingulin is coordinated with the start of stratification and differentiation in corneal epithelial cells: retinoic acid reversibly disrupts epithelial barrier Expression of claudins -2 and -4 and cingulin is coordinated with the start of stratification and differentiation in corneal epithelial cells: retinoic acid reversibly disrupts epithelial barrier [J] . Eber Gómez-Flores, Erika Sánchez-Guzmán, Arturo González-Robles, Biology Open . 2013 ,第2期

机译：claudins -2和-4和cercingulin的表达与角膜上皮细胞分层和分化的开始相协调：视黄酸可逆地破坏上皮屏障的表达claudins -2和-4和cingcingulin与角膜上皮细胞的分层和分化的开始相协调角膜上皮细胞：维甲酸可逆地破坏上皮屏障claudins -2和-4和cingulin的表达与角膜上皮细胞分层和分化的开始相协调：维甲酸可逆地破坏上皮屏障
4. Dendrimer crosslinked collagen hydrogels modified with YIGSR peptide and their effects on cellular behaviors of human corneal epithelial cell line and nerve regeneration [C] . Duan, X, McLaughlin, Society for Biomaterials Transaction Annual Meeting vol.29 pt.2 . 2006

机译：YIGSR肽修饰的树状聚合物交联胶原水凝胶及其对人角膜上皮细胞系细胞行为和神经再生的影响
5. Developmental corneal innervation: Regulation by multiple factors and interactions between nerves and specialized corneal epithelial cells. [D] . Kubilus, James Kenneth. 2009

机译：发育性角膜神经支配：受多种因素的调节以及神经与特定角膜上皮细胞之间的相互作用。
6. Ultrasound Treatment Increases Transfection Efficiency of Low Molecular Weight Chitosan in Fibroblasts but Not in KB Cells [O] . Ureporn Kedjarune-Leggat, Chanyapat Supaprutsakul, Wilaiwan Chotigeat -1

机译：超声处理可提高成纤维细胞中低分子量壳聚糖的转染效率但不能提高KB细胞的转染效率
7. Chitosan Modification of Adenovirus to Modify Transfection Efficiency in Bovine Corneal Epithelial Cells [O] . Wang, I-Jong, Jhuang, Min-Chao, Chen, Yu-Hsin, 2010

机译：腺病毒的壳聚糖修饰以修饰牛角膜上皮细胞的转染效率

Chitosan Modification of Adenovirus to Modify Transfection Efficiency in Bovine Corneal Epithelial Cells

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