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Prevention and Treatment of Influenza with Hyperimmune Bovine Colostrum Antibody

机译:用超免疫牛初乳抗体预防和治疗流感

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摘要

BackgroundDespite the availability of specific vaccines and antiviral drugs, influenza continues to impose a heavy toll on human health worldwide. Passive transfer of specific antibody (Ab) may provide a useful means of preventing or treating disease in unvaccinated individuals or those failing to adequately seroconvert, especially now that resistance to antiviral drugs is on the rise. However, preparation of appropriate Ab in large scale, quickly and on a yearly basis is viewed as a significant logistical hurdle for this approach to control seasonal influenza.
机译:背景技术尽管有特定的疫苗和抗病毒药物,但流感继续给全世界的人类健康造成沉重打击。被动转移特异性抗体(Ab)可能为预防或治疗未接种疫苗的个体或未能进行充分血清学转化的个体提供有效的疾病预防手段,尤其是现在对抗病毒药物的耐药性正在上升。然而,对于这种控制季节性流感的方法而言,大规模,快速且每年一次地制备适当的抗体被视为重大的物流障碍。

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