Assembly of Microtubules and Actomyosin Rings in the Absence of Nuclei and Spindle Pole Bodies Revealed by a Novel Genetic Method

摘要

BackgroundThe nucleus and the centrosomes (spindle pole bodies; SPBs in yeast) are believed to play key roles in the organization of various cellular structures, such as the actomyosin ring and microtubules. The ability to generate cells lacking nuclei and centrosomes (SPBs) is key to the elucidation of the role of these structures in various cellular processes.