1854. Effective Antimicrobial Stewardship for Outpatient Parenteral Antimicrobial Therapy (OPAT): Nationwide Experience in Infectious Disease Physician Infusion Centers

摘要

BackgroundAntimicrobial stewardship (AS) is an important factor in combatting antimicrobial resistance and optimizing clinical outcomes, especially in the outpatient setting. With no AS guidelines in the United States for OPAT, we developed an antimicrobial stewardship program (ASP) for OPAT in 2016, which was piloted and applied to Infectious Disease practices and infusion centers. The program was expanded and assessed nationally in additional centers in 2017, adding appropriateness of empiric therapy (tx), supervision of first doses of antimicrobials, compliance with tx regimen, appropriate tx changes and staff education.