648. Urinary Tract-Associated Escherichia coli Bacteraemia Strains Are Genetically More Virulent than Those Originating From Non-urinary and Neutropaenic Infective Foci

摘要

Background Escherichia coli is the leading cause of bacteremia with multi-drug-resistant strains proving increasingly problematic. Knowledge of the strain diversity associated with site-specific infections will inform the development of new preventative strategies, e.g. vaccines. We hypothesized that virulence factor (VF) scores of bacteremia strains from neutropenia patients with unknown infective foci (NPUIF—likely due to bowel translocation) would be lower than those from immunocompetent patients.