2404. Telavancin (TLV) and Vancomycin (VAN) Activity and Impact on Mechanical Properties When Incorporated into Orthopedic Bone Cement

摘要

BackgroundTo increase available antibiotics for local administration in total joint replacements, this study investigated TLV and VAN added to Palacos® bone cement. Mechanical properties and antimicrobial activity of eluted antibiotics on common causative orthopedic implant pathogens were assessed.