184. Channeling Alexander Fleming: Efficacy of Penicillin (PCN) to Treat Staphylococcus aureus (SA) Bacteremia

摘要

BackgroundUp to 20% of SA isolates in the United States are penicillin-susceptible (PSSA); however, treatment with penicillin has been discouraged because of concern that routine testing may miss strains that have the capacity to produce clinically significant ß-lactamase in vivo. We performed a retrospective analysis to determine whether PCN therapy for the treatment of PSSA bacteremia was of comparable efficacy and safety to standard therapies.