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Criterion values for urine-specific gravity and urine color representing adequate water intake in healthy adults

机译:尿比重和尿色的标准值代表健康成年人的适量饮水

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摘要

Growing evidence suggests a distinction between water intake necessary for maintaining a euhydrated state, and water intake considered to be adequate from a perspective of long-term health. Previously, we have proposed that maintaining a 24-h urine osmolality (UOsm) of ⩽500 mOsm/kg is a desirable target for urine concentration to ensure sufficient urinary output to reduce renal health risk and circulating vasopressin. In clinical practice and field monitoring, the measurement of UOsm is not practical. In this analysis, we calculate criterion values for urine-specific gravity (USG) and urine color (UCol), two measures which have broad applicability in clinical and field settings. A receiver operating characteristic curve analysis performed on 817 urine samples demonstrates that a USG ⩾1.013 detects UOsm>500 mOsm/kg with very high accuracy (AUC 0.984), whereas a subject-assessed UCol⩾4 offers high sensitivity and moderate specificity (AUC 0.831) for detecting UOsm >500 m Osm/kg.
机译:越来越多的证据表明,从保持长期健康的角度来看,维持正常水分状态所需的摄水量与认为足够的摄水量之间存在区别。以前,我们曾建议将24小时尿渗透压(UOsm)维持在⩽500mOsm / kg是理想的尿液浓缩目标,以确保充足的尿量以降低肾脏健康风险和循环加压素。在临床实践和现场监测中,UOsm的测量是不实际的。在此分析中,我们计算了尿比重(USG)和尿色(UCol)的标准值,这两种方法在临床和现场环境中具有广泛的适用性。对817个尿液样本进行的接收器工作特性曲线分析表明,USG⩾1.013能够以非常高的准确度(AUC 0.984)检测到UOsm> 500mmOsm / kg(AUC 0.984),而受试者评估的UCol⩾4提供了高灵敏度和中等特异性(AUC 0.831 ),以检测UOsm> 500 m Osm / kg。

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