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Surgical management of tuberculum sellae meningiomas: involvement of the optic canal and visual outcome

机译:蝶鞍性脑膜瘤的外科治疗:视神经管受累和视觉结果

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摘要

>Objective: To present a large series of surgically treated tuberculum sellae meningiomas with particular regard to involvement of the optic canal and visual outcome. >Methods: A retrospective analysis was done on 53 patients (40 female) with meningiomas originating from the tuberculum sellae who underwent surgery between 1991 and 2002. The standard surgical approach consisted of pterional craniotomy. Sixteen meningiomas extended posteriorly onto the diaphragma sella, 29 anteriorly to the planum sphenoidale, and 19 to the anterior clinoid process. Thirty seven tumours involved the optic canal, three bilaterally. Follow up ranged from 6 to 108 months (mean 29.9 months). >Results: Total macroscopic resection was achieved in 48 patients. Median tumour size was 2.6 cm. Postoperatively, visual acuity improved in 20 patients and deteriorated in seven. Preoperative and postoperative visual acuity worsened with increasing duration of preoperative symptoms and with increasing age. Extension into the intraconal space was a negative predictor. However, tumour size did not influence visual acuity. Recurrence occurred in two cases (21 and 69 months postoperatively). Two patients died from causes unrelated to the tumour. >Conclusions: In the majority of patients with tuberculum sellae meningiomas, total resection may be achieved through a pterional approach with minimal complications.
机译:>目的:介绍一系列经过外科手术治疗的蝶鞍状脑膜瘤,特别涉及视神经管的侵犯和视觉结果。 >方法:回顾性分析了1991年至2002年之间接受手术治疗的53例来自蝶鞍的脑膜瘤患者(40例女性)。标准手术方法为颅骨开颅手术。十六个脑膜瘤向后延伸至蝶diaphragm上,向前延伸至蝶骨29个,向前斜突前19个。视神经管肿瘤37例,双侧肿瘤3例。随访时间为6到108个月(平均29.9个月)。 >结果:48例患者全部完成了宏观切除术。中位肿瘤大小为2.6厘米。术后视力改善20例,恶化7例。术前和术后视力随着术前症状持续时间的增加和年龄的增加而恶化。扩展到圆锥内腔是一个负面的预测因素。但是,肿瘤的大小并不影响视力。 2例(术后21个月和69个月)复发。两名患者死于与肿瘤无关的原因。 >结论:在大多数蝶鞍型脑膜瘤患者中,可以通过翼状approach肉术实现全切除,并发症最少。

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