The kinesin-like protein Pavarotti functions noncanonically to regulate actin dynamics

摘要

The centralspindlin complex, comprising Tumbleweed RhoGAP and kinesin-like Pavarotti proteins, associates with microtubules during cytokinesis. Nakamura et al. show that Pavarotti has centralspindlin complex–independent functions, binds directly to actin, and regulates actin dynamics during cell wound repair and oogenesis.