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Anencephaly: Do the Pregnancy and Maternal Characteristics Impact the Pregnancy Outcome?

机译:无脑:怀孕和母亲特征是否会影响怀孕结果?

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摘要

Objective. To describe the characteristics of obstetric and perinatal outcome of a group of pregnancies complicated by an anencephalic fetus. Methods. Observational study including anencephalic fetuses, divided into groups according to the evolution of pregnancy: elective termination of pregnancy ETP; stillbirths (SBs); live births (LBs), and loss of follow-up. After a univariate description of the sample, some variables were compared using statistical tests. Results. 180 anencephalic fetuses were included. The mean maternal age was 25.3 years. In 71 fetuses (39%) were found additional anomalies. Comparing the groups, no statistical differences in maternal age (P = 0.5315), parity (P = 0.6070), number of previous abortion (P = 0.7464), fetal sex (P = 0.0502) and additional anomalies (P = 0.186) were found. Among those fetuses whose parents opted for continuation of pregnancy (n = 53), 20 spontaneous intrauterine deaths occurred (38%) and 33 were live births (62%). The average postnatal survival time was 51 minutes. There was no association between survival time and gestational age (P = 0.6125) or the presence of additional malformations (P = 0.1948). Conclusion. Results presented here could contribute to a better understanding of the natural history of this malformation, allowing obstetricians a more detailed discussion with the families.
机译:目的。描述一组妊娠合并无脑胎儿的产科和围产期结局的特征。方法。观察性研究包括无脑胎儿,根据妊娠的进展分为几组:选择性终止妊娠ETP;死产(SBs);活产(LBs),以及失去随访。在对样本进行单变量描述之后,使用统计检验比较了一些变量。结果。包括180名无脑胎儿。产妇平均年龄为25.3岁。在71例胎儿(占39%)中发现了其他异常情况。比较各组,未发现产妇年龄(P = 0.5315),胎次(P = 0.6070),先前流产次数(P = 0.7464),胎儿性别(P = 0.0502)和其他异常情况(P = 0.186)的统计差异。 。在其父母选择继续妊娠的胎儿中(n = 53),发生了20例自发性子宫内死亡(38%),其中33例是活产(62%)。产后平均生存时间为51分钟。存活时间与胎龄(P = 0.6125)或其他畸形(P = 0.1948)之间没有关联。结论。这里介绍的结果可能有助于更好地了解这种畸形的自然史,从而使产科医生可以与家人进行更详细的讨论。

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