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  • 机译 减少肥胖症的社会和种族/种族差异的实用研究策略
    • 作者:L G RosasR S Stafford
    • 刊名:International Journal of Obesity Supplements
    • 2012年第Suppl 1期
    摘要:Adult and childhood obesity and related adverse outcomes are most common among racial/ethnic minorities and socio-economically disadvantaged populations in the United States. Research approaches to obesity developed in mainstream populations and deploying new information technologies may exacerbate existing disparities in obesity. Current obesity management and prevention research priorities will not maximally impact this critical problem unless investigators explicitly focus on discovering innovative strategies for preventing and managing obesity in the disadvantaged populations that are most affected. On the basis of our research experience, four key research approaches are needed: (1) elucidating the underlying social forces that lead to disparities; (2) directly involving community members in the development of research questions and research methods; (3) developing flexible strategies that allow tailoring to multiple disadvantaged populations; and (4) building culturally and socio-economically tailored strategies specifically for populations most affected by obesity. Our experience with a community-based longitudinal cohort study and two health-center-based clinical trials illustrate these principles as a contrast to traditional research priorities that can inadvertently worsen existing social inequities. If obesity research does not directly address healthcare and health-outcome disparities, it will contribute to their perpetuation.
  • 机译 肥胖的治疗匹配:确定社会心理和行为干预成分的中介者
    • 作者:M Kiernan
    • 刊名:International Journal of Obesity Supplements
    • 2012年第Suppl 1期
    摘要:In light of the limited long-term success of obesity treatments, it is tempting to consider the elusive goal of ‘treatment matching', in which characteristics of individuals are optimally matched to targeted treatments to improve success. Previous frameworks for treatment matching in obesity have primarily focused on basic physiological characteristics, such as initial degree of overweight, and on treatment intensity, such as stepped-care alternatives (self-help manuals, group support, medication and surgery). Few studies have empirically evaluated the success of these frameworks. Given recent advances in genomics, neuroscience and other fields, both the breadth of domains and combinations of individuals' characteristics that could be used for treatment matching have increased markedly. Although the obesity field seems poised to build on these advances, a crucial challenge remains regarding the treatments themselves. Ultimately, the success of treatment matching will rely on identifying treatment intervention components with well-differentiated and empirically supported mediators, that is, clear insights into how intervention components work. Here we examine the scope of this challenge specifically for the design of efficacious psychosocial and behavioral intervention components, and identify areas for future research.
  • 机译 久坐的行为:改变目标,评估挑战
    • 作者:M Rosenberger
    • 刊名:International Journal of Obesity Supplements
    • 2012年第Suppl 1期
    摘要:Sedentary behavior is not a new topic, but trying to examine the direct links between sedentary behavior and health outcomes, independent of time spent in moderate- and vigorous-intensity physical activity, is a relatively new addition to the relationships between physical activity and health. Defining sedentary behavior as a risk factor and target for intervention opens up novel avenues for disease prevention and health promotion. The relationship between sedentary behavior and obesity is complex and not well understood, but the increased risk of disease due to sedentary behavior may be even greater in obese patients. Objective measurement of sedentary behavior is an important link in being able to understand the real effects of being sedentary, and a few measurement devices are described. Interventions targeting sedentary behavior should reduce total sedentary time, break long bouts of sitting with intermittent activity and encourage light-intensity activity throughout the day. New technologies can both measure and deliver an intervention aimed at reducing sitting time, the most common category of sedentary behavior. An optimal activity profile will include minimal amounts of sedentary behavior, in addition to regular physical activity and healthy sleep patterns.
  • 机译 在特定人群(高中)中预防肥胖
    摘要:Background:A challenge for the widespread dissemination of Internet-based programs designed to produce weight maintenance/loss in defined (high school) populations is to adapt them to local needs and interests, whereas demonstrating effectiveness and salience for both universal and targeted populations.
  • 机译 健康体重中心:应对儿童肥胖的学术医学中心
    • 作者:T N RobinsonK M Kemby
    • 刊名:International Journal of Obesity Supplements
    • 2012年第Suppl 1期
    摘要:Childhood obesity represents a worldwide medical and public health challenge. Academic medical centers cannot avoid the effects of the obesity epidemic, and must adopt strategies for their academic, clinical and public policy responses to childhood obesity. The Center for Healthy Weight at Stanford University and Lucile Packard Children's Hospital at Stanford provides an example and model of one such strategy. The design provides both breadth and depth through six cores: Research, Patient Care, Community Programs, Advocating for Public Policy Change, Training and Professional Education, and the Healthy Hospital Initiative. The Center and its cores are designed to facilitate interdisciplinary collaboration across the university, medical school, children's hospital and surrounding community. The foci of these cores are likely to be relevant to almost any academic medical center's mission and functions.
  • 机译 填补超重和肥胖患者体重管理中的治疗空白
    • 作者:N Gesundheit
    • 刊名:International Journal of Obesity Supplements
    • 2012年第Suppl 1期
    摘要:Approximately two out of three adult Americans are overweight or obese. Despite widespread recognition of this disorder, there has been little progress in the past 20 years in finding effective noninvasive treatments for weight loss. The consequences of obesity are increasingly well recognized and include increases in blood pressure, plasma lipids, the onset of type 2 diabetes, sleep apnea, asthma, osteoarthritis and a variety of cancers. Obesity can increase the rate of pregnancy complications and fetal malformations in normoglycemic women. Current medical approaches to obesity, including intensive lifestyle interventions and drug therapies, have been successful in achieving modest weight loss of 4–7%, less than the 1998 NIH Guidelines target of 10%. Surgical approaches, including laparoscopic adjustable gastric banding, vertical banded gastroplasty and Roux-en-Y gastric bypass, are much more successful, achieving weight loss of 15–50%. A treatment gap therefore exists in the management of obese and overweight patients, because many patients desire and would receive great health benefits by achieving weight loss of 7–15%. This review will discuss the dilemma of the treatment gap and explore possible ways by which it may be filled in the future by the use of innovative approaches.
  • 机译 开发多学科体重管理中心的概念基础和临床原理
    • 作者:M K Artandi
    • 刊名:International Journal of Obesity Supplements
    • 2012年第Suppl 1期
    摘要:Overweight (body mass index (BMI) 25 kg m−2) or obesity (BMI 30>kg m−2) affects more than two-thirds of Americans. Overweight and obesity are commonly associated with multiple coexisting conditions, such as hypertension, diabetes, dyslipidemia, cardiovascular disease, obstructive sleep apnea and cancer. Lifestyle modification can induce a modest weight loss, which is associated with the prevention or improvement of many of these comorbidities. A combination of diet, exercise and behavioral therapy is considered the cornerstone of treatment for all overweight and obese individuals. As the etiology and therapy of obesity is complex, what is needed for these patients is a multidisciplinary clinic where specialists from different disciplines share their knowledge and participate in the treatment of the obese patient.
  • 机译 减肥手术:谁和何时?
    • 作者:N A LodhiaJ M Morton
    • 刊名:International Journal of Obesity Supplements
    • 2012年第Suppl 1期
    摘要:Over two-thirds of the United States is overweight or obese, and over 5% of the country is morbidly obese. Numerous public health preventative measures have been established to help battle this public health epidemic. Surgical obesity treatment, although now gaining popularity, has been an underutilized treatment option for obesity. Patients with a body mass index (BMI) of >40 or >35 kg m−2 with two or more comorbid conditions are eligible for bariatric surgery. Currently, the three most popular bariatric surgeries are Roux-en-y gastric bypass, sleeve gastrectomy and gastric banding procedures, all overwhelmingly performed laparoscopically. The purpose of this article is to discuss the heterogeneity of bariatric surgery. In our practice, among 834 patients operated over a 4-year period (2006–2010), patients were of an average age of 45 years (16–73 years), 80.4% were female patients, 82.5% had private insurance, 61% were White, 17% were Hispanic and 9% were Black. Patients had an average BMI of 46.2 kg m−2 (30.1–75.3 kg m−2), waist circumference of 133.6 cm (68.6–207.8 cm) and four preoperative comorbidities (0–11 comorbidities). Variation exists in surgeon practice patterns for preoperative weight-loss recommendations and complication rates based on surgery case volume. Despite variation in patient, surgeon and hospital characteristics, bariatric surgery outcomes are generally highly safe and effective.
  • 机译 委员会
    • 作者:
    • 刊名:International Journal of Obesity Supplements
    • 2011年第Suppl 1期
    摘要:
  • 机译 科学程序
    • 作者:
    • 刊名:International Journal of Obesity Supplements
    • 2011年第Suppl 1期
    摘要:
  • 机译 摘要
    • 作者:
    • 刊名:International Journal of Obesity Supplements
    • 2011年第Suppl 1期
    摘要:
  • 机译 作者索引
    • 作者:
    • 刊名:International Journal of Obesity Supplements
    • 2011年第Suppl 1期
    摘要:

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