ACE gene polymorphism is associated with COPD and COPD with pulmonary hypertension: a meta-analysis

摘要

PurposeAngiotensin-converting enzyme (ACE) gene I/D polymorphism has been studied in relation to the susceptibility to COPD and COPD with pulmonary hypertension (PH) with inconclusive results. We performed the first comprehensive meta-analysis to evaluate accurately the association between the ACE gene polymorphism and the risk of COPD.