Tiotropium HandiHaler® in the treatment of COPD: A safety review

摘要

BackgroundTiotropium is a long-acting inhaled anticholinergic developed for the treatment of chronic obstructive pulmonary disease (COPD) and has been available since 2002. We sought to update an evaluation of the safety of tiotropium in the HandiHaler^® formulation as significant clinical trial data have become available over time.