The therapeutic effect in gliomas of nanobubbles carrying siRNA combined with ultrasound-targeted destruction

机译：携带siRNA的纳米气泡联合超声靶向破坏对神经胶质瘤的治疗作用

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BackgroundNanobubbles (NBs) combined with ultrasound-targeted destruction (UTD) have become promising potential carriers for drug or siRNA delivery. Due to their nano-size, NBs could penetrate tumor blood vessels and accumulate in intercellular spaces so that “sonoporation” induced by UTD would act directly on the tumor cells to increase cell membrane permeability.

机译：背景纳米气泡（NBs）与超声靶向破坏（UTD）结合已成为有望用于药物或siRNA输送的潜在载体。由于它们的纳米尺寸，NB可以穿透肿瘤血管并积聚在细胞间空间中，因此由UTD诱导的“ sonoporation”将直接作用于肿瘤细胞以增加细胞膜通透性。

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期刊名称 International Journal of Nanomedicine
作者
Wenbin Cai; Wei Lv; Yang Feng; Hengli Yang; Yajun Zhang; Guodong Yang; Yunyou Duan; Jia Wang;
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作者单位

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年(卷),期 2018(13),-1
年度 2018
页码 6791–6807
总页数 17
原文格式 PDF
正文语种
中图分类生化遗传学;生化药理学;
关键词
nanobubbles ultrasound siRNA glioma;

机译：纳米气泡;超声;siRNA;神经胶质瘤;

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专利

1. The therapeutic effect in gliomas of nanobubbles carrying siRNA combined with ultrasound-targeted destruction [J] . Wenbin Cai, Wei Lv, Yang Feng, International Journal of Nanomedicine . 2018,第3期

机译：携带siRNA的纳米气泡联合超声靶向破坏对神经胶质瘤的治疗作用
2. Apatinib-loaded lipid nanobubbles combined with ultrasound-targeted nanobubble destruction for synergistic treatment of HepG2 cells in vitro [J] . Yuhang Tian, Zhao Liu, Lei Zhang, OncoTargets and therapy . 2018,第2期

机译：加入的脂质纳米泡脂质结合超声靶向纳米柔臼破坏，用于体外协同治疗HepG2细胞
3. Ultrasound-sensitive siRNA-loaded nanobubbles formed by hetero-assembly of polymeric micelles and liposomes and their therapeutic effect in gliomas [J] . YinT., WangP., LiJ., Biomaterials . 2013,第18期

机译：高分子胶束和脂质体杂合形成的超声敏感siRNA纳米气泡及其在神经胶质瘤中的治疗作用
4. Therapeutic Effect of Attenuated Salmonella Carrying SiRNA-STAT3 Plasmid on Transplanted Prostate Cancer in Mice [C] . Zhongyi Cong, Yue Zhou, Shuhan Zhou, SREE Workshop on Medical Materials and Engineering . 2012

机译：减毒沙门氏菌携带siRNA-Stat3质粒对小鼠移植前列腺癌的治疗作用
5. Using Patient-Derived Gliomaspheres to Molecularly Characterize and Dissect Distinctive Traits of Isocitrate Dehydrogenase 1 Mutant Gliomas for Therapeutic Benefit. [D] . Garrett, Matthew Clark. 2016

机译：使用患者衍生的胶质细胞球分子表征和解剖异柠檬酸脱氢酶1突变胶质瘤的显着特征，以达到治疗目的。
6. Apatinib-loaded lipid nanobubbles combined with ultrasound-targeted nanobubble destruction for synergistic treatment of HepG2 cells in vitro [O] . Yuhang Tian, Zhao Liu, Lei Zhang, 2018

机译：载有阿帕替尼的脂质纳米泡与超声靶向的纳米泡破坏联合体外协同治疗HepG2细胞
7. The therapeutic effect in gliomas of nanobubbles carrying siRNA combined with ultrasound-targeted destruction [O] . Wenbin Cai, Wei Lv, Yang Feng, 2018

机译：纳米博根胶质瘤的治疗效果与超声靶向破坏结合使用

The therapeutic effect in gliomas of nanobubbles carrying siRNA combined with ultrasound-targeted destruction

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