A novel folate-modified self-microemulsifying drug delivery system of curcumin for colon targeting

机译：一种新型的叶酸修饰的姜黄素自微乳化递药系统用于结肠靶向

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摘要

BackgroundThe objective of this study was to prepare, characterize, and evaluate a folate-modified self-microemulsifying drug delivery system (FSMEDDS) with the aim to improve the solubility of curcumin and its delivery to the colon, facilitating endocytosis of FSMEDDS mediated by folate receptors on colon cancer cells.

机译：背景本研究的目的是制备，表征和评估叶酸修饰的自微乳化药物递送系统（FSMEDDS），旨在提高姜黄素的溶解度及其向结肠的递送，从而促进由叶酸受体介导的FSMEDDS的内吞作用在结肠癌细胞上。

著录项

期刊名称 International Journal of Nanomedicine
作者
Lin Zhang; Weiwei Zhu; Chunfen Yang; Hongxia Guo; Aihua Yu; Jianbo Ji; Yan Gao; Min Sun; Guangxi Zhai;
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作者单位

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年(卷),期 2012(7),-1
年度 2012
页码 151–162
总页数 12
原文格式 PDF
正文语种
中图分类生化遗传学;生化药理学;
关键词
curcumin SMEDDS folate receptor colon targeting;

机译：姜黄素;SMEDDS;叶酸受体;靶向结肠;

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专利

1. A novel folate-modified self-microemulsifying drug delivery system of curcumin for colon targeting [J] . Lin Zhang, Weiwei Zhu, Chunfen Yang, International Journal of Nanomedicine . 2012,第1期

机译：一种新型的叶酸修饰的姜黄素自微乳化递药系统，用于结肠靶向
2. Co-delivery of natural metabolic inhibitors in a self-microemulsifying drug delivery system for improved oral bioavailability of curcumin [J] . GrillA.E., KoniarB., PanyamJ. Drug delivery and translational research . 2014,第4期

机译：在自微乳化药物输送系统中共同输送天然代谢抑制剂，以改善姜黄素的口服生物利用度
3. Alginate-Based Composite Sponges as Gastroretentive Carriers for Curcumin-Loaded Self-Microemulsifying Drug Delivery Systems [J] . Arpa Petchsomrit, Namfa Sermkaew, Ruedeekorn Wiwattanapatapee Scientia pharmaceutica . 2017,第1期

机译：海藻酸盐基复合海绵作为姜黄素负载型自微乳化药物递送系统的胃滞留载体
4. Polymer mixtures as colon targeted drug delivery systems [C] . Mario Helmis, Mont Kumpugdee-Vollrath International Conference on Manufacturing Science and Engineering . 2013

机译：聚合物混合物作为结肠靶向药物递送系统
5. Development and characterization of a solid self-microemulsifying drug delivery system (SMEDDS) of albendazole and evaluation of oral bioavailability in rabbits. [D] . Mukherjee, Tusharmouli. 2010

机译：阿苯达唑固体自微乳化药物递送系统（SMEDDS）的开发和表征以及兔口服生物利用度的评估。
6. CO-DELIVERY OF NATURAL METABOLIC INHIBITORS IN A SELF-MICROEMULSIFYING DRUG DELIVERY SYSTEM FOR IMPROVED ORAL BIOAVAILABILITY OF CURCUMIN [O] . Alex E. Grill, Brenda Koniar, Jayanth Panyam -1

机译：天然代谢抑制剂在自体微丸化药物递送系统中的共递送可提高姜黄素的口服生物利用度
7. A novel folate-modified self-microemulsifying drug delivery system of curcumin for colon targeting [O] . Zhang, Lin, Zhu, Weiwei, Yang, Chunfen, 2012

机译：一种新型的叶酸修饰的姜黄素自微乳化递药系统，用于结肠靶向

A novel folate-modified self-microemulsifying drug delivery system of curcumin for colon targeting

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