A novel haemostatic agent based on self-assembling peptides in the setting of nasal endoscopic surgery a case series

摘要

IntroductionRecently, a novel purely synthetic topical haemostatic agent (PuraStat^®) has been proposed in surgery based on the self-assembling tendency of some repeating peptide sequences. This transparent, ready to use hydrogel appears suitable for use in FEES with low rates of post-operative re-bleeding and adhesion formation.A first series of 60 patients experiencing endonasal powered turbinoplasty across various hospitals in Sydney using PuraStat^® was observed for postoperative re-bleeding and adhesion formation.