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Comparison of Frequency Bands Using Spectral Entropy for Epileptic Seizure Prediction

机译:使用频谱熵比较频段进行癫痫发作的预测

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摘要

Introduction. Under the hypothesis that the uncontrolled neuronal synchronization propagates recruiting more and more neurons, the aim is to detect its onset as early as possible by signal analysis. This synchronization is not noticeable just by looking at the EEG, so mathematical tools are needed for its identification. Objective. The aim of this study is to compare the results of spectral entropies calculated in different frequency bands of the EEG signals to decide which band may be a better tool to predict an epileptic seizure. Materials and Methods. Invasive ictal records were used. We measured the Fourier spectrum entropy of the electroencephalographic signals 4 to 32 minutes before the attack in low, medium and high frequencies. Results. The high-frequency band shows a markedly rate of increase of the entropy, with positive slopes and low correlation coefficient. The entropy rate of growth in the low-frequency band is practically zero, with a correlation around 0.2 and mostly positive slopes. The mid-frequency band showed both positive and negative slopes with low correlation. Conclusions. The entropy in the high frequencies could be predictor, because it shows changes in the previous moments of the attack. Its main problem is the variability, which makes it difficult to set the threshold that ensures an adequate prediction.
机译:介绍。在不受控制的神经元同步传播招募越来越多的神经元的假设下,目的是通过信号分析尽可能早地检测其发作。仅通过查看EEG并不会注意到这种同步,因此需要数学工具对其进行识别。目的。这项研究的目的是比较在脑电信号的不同频带中计算出的频谱熵的结果,以确定哪个频带可能是预测癫痫发作的更好工具。材料和方法。使用侵入性的发作记录。我们在发作前4至32分钟以低频,中频和高频测量了脑电图信号的傅立叶频谱熵。结果。高频带显示出熵的明显增加率,具有正斜率和低相关系数。低频频段的熵增长率实际上为零,相关系数约为0.2,且大多为正斜率。中频带显示正斜率和负斜率,相关性较低。结论。高频中的熵可能是预测因素,因为它显示了攻击前一刻的变化。它的主要问题是可变性,这使得难以设置阈值以确保足够的预测。

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