A161 EVALUATING THE DIFFERENCES IN PERCEIVED STRESS AMONG NON-INFLAMMATORY AND INFLAMMATORY IBD FLARES

摘要

BackgroundThe presence and severity of symptoms in IBD correlate poorly with the degree of inflammatory activity, especially in Crohn’s disease (CD). Psychological factors, including perceived stress and mood disruption are associated with symptom activity. This relationship is bidirectional with increased symptoms predicting later increased perceived stress and vice versa. It is unclear whether the association between high perceived stress and active symptoms is weighted more towards high perceived stress being associated with symptomatic activity in individuals and no concurrent active inflammation than it would be in persons with increased symptoms and evidence of intestinal inflammation.