A141 CONCORDANCE BETWEEN TUBERCULIN SKIN TEST AND INTERFERON GAMMA RELEASE ASSAY FOR LATENT TUBERCULOSIS SCREENING IN INFLAMMATORY BOWEL DISEASE (META-ANALYSIS).

摘要

BackgroundScreening for latent tuberculosis infection (LTBI) is mandatory prior to initiating anti-tumor necrosis factor (anti-TNF) medications. New guidelines recommend interferon-gamma release assays as first line screening method for the general population. Studies have provided conflicting evidence on the performance of interferon-gamma release assays (IGRAs), compared to tuberculin skin test (TST) in inflammatory bowel disease (IBD) patients. We assessed the concordance of these two tests in IBD patients and the effect of immunosuppression on their performance.