A color discriminating broad range cell staining technology for early detection of cell transformation

摘要

Background:Advanced diagnostic tools stand today at the heart of successful cancer treatment. CellDetect^® is a new histochemical staining technology that enables color discrimination between normal cells and a wide variety of neoplastic tissues. Using this technology, normal cells are colored blue/green, while neoplastic cells color red. This tinctorial difference coincides with clear morphological visualization properties, mainly in tissue samples. Here we show that the CellDetect^® technology can be deployed to distinguish normal cells from transformed cells and most significantly detect cells in their early pre-cancerous transformed state.