Safety Science and Sales: A Request for Valid Clinical Trials to Assess New Devices for Endovascular Treatment of Intracranial Aneurysms

摘要

Many advances in neurointerventional procedures depend on the development of new devices. Endovascular approaches to neurovascular diseases are still young. They do not attract the same level of financial support as other fields. They should nevertheless be developed along rigorous, scientific steps, from valid laboratory and animal studies to well-designed randomized clinical trials. Ideally, valid trials should address important clinical dilemmas, such as the preventive treatment of unruptured aneurysms, as well as precede the widespread use of new devices.