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Enhanced inhibition of tumor growth using TRAIL-overexpressing adipose-derived stem cells in combination with the chemotherapeutic agent CPT-11 in castration-resistant prostate cancer

机译：使用Trail-InveRexpring衍生的干细胞与抗阉割前列腺癌中的化学治疗剂CPT-11组合使用Trail过度表达脂肪衍生的干细胞增强抑制肿瘤生长

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摘要

This study investigated the inhibition of tumor growth in castrate-resistant prostate cancer (CRPC)-bearing mice by tumor necrosis factor–related apoptosis-inducing ligand (TRAIL)-overexpressing adipose-derived stem cells (ADSCs) (hTERT-ADSC.sTRAIL), which was enhanced by combined treatment with CPT-11.

机译：本研究调查了抑制肿瘤生长在抗胆汁抗癌前列腺癌（CRPC） - BEAKING小鼠中抑制肿瘤坏死因子相关的凋亡诱导配体（TRAIL）-Overxcressing脂肪衍生的干细胞（ADSC）（HTERT-ADSC.STRAIL），通过CPT-11的组合治疗增强。

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期刊名称 Prostate International
作者
Jae Heon Kim; Eunjung Oh; Yong Seok Han; Sang Hun Lee; Yun Seob Song;
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作者单位

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年(卷),期 2021(9),1
年度 2021
页码 31–41
总页数 11
原文格式 PDF
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关键词

机译：前列腺癌;小径;CPT-11;

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专利

1. Enhanced inhibition of tumor growth using TRAIL-overexpressing adipose-derived stem cells in combination with the chemotherapeutic agent CPT-11 in castration-resistant prostate cancer [J] . Jae Heon Kim, Eunjung Oh, Yong Seok Han, Prostate International . 2021,第1期

机译：使用Trail-InveRexpring衍生的干细胞与抗阉割前列腺癌中的化学治疗剂CPT-11组合使用Trail过度表达脂肪衍生的干细胞增强抑制肿瘤生长
2. Inhibition of constitutively activated phosphoinositide 3-kinase/AKT pathway enhances antitumor activity of chemotherapeutic agents in breast cancer susceptibility gene 1-defective breast cancer cells [J] . YiY.W., KangH.J., KimH.J., Molecular Carcinogenesis . 2013,第9期

机译：抑制组成型活化的磷酸肌醇3-激酶/ AKT途径增强了乳腺癌易感基因1缺陷型乳腺癌细胞中化学治疗剂的抗肿瘤活性。
3. Influence of the prodrugs 5-fluorocytosine and CPT-11 on ovarian cancer cells using genetically engineered stem cells: tumor-tropic potential and inhibition of ovarian cancer cell growth [J] . Ki Yon Kim Seung U. Kim Peter C. K. Leung1 Eui Bae Jeung and Kyung Chul Choi Cancer science. . 2010,第4期

机译：基因工程干细胞对前药5-氟胞嘧啶和CPT-11对卵巢癌细胞的影响：趋于肿瘤的潜能和对卵巢癌细胞生长的抑制
4. Comparison of Employing WI-38 and NIH/3T3 Cells for Evaluation of Chemotherapeutic Index and Growth Inhibition Values for Pancreatic Cancer Cell Lines for Group IVB Metallocene and Group VA Metal-Containing Polymers Derived from Glycyrrhetinic Acid, 3,5-Pyridine-dicarboxylic Acid, and Histamine [C] . Michael R. Roner, Charles E. Carraher, Alisa Moric, American Chemical Society., Division of Polymeric Materials : Science and Engineering., Meeting . 2013

机译：使用Wi-38和NIH / 3T3细胞对IVB茂金属组胰腺癌细胞系的化学治疗指数和生长抑制值的比较和衍生自甘草酸，3,5-吡啶 - 二羧酸的基团的含金醛和含金属聚合物的胰腺癌细胞系的生长抑制值。和组胺
5. Design and Synthesis of Pyrimidine Based Heterocycles as Potential Anti-cancer Agents with Combination Chemotherapeutic Potential or Targeted One Carbon Metabolism Inhibition and Anti-opportunistic Agents [D] . Doshi, Arpit. 2019

机译：基于嘧啶的杂环作为潜在抗癌剂的设计与合成，具有组合化疗潜力或靶向一种碳代谢抑制和抗机会性药物
6. Inhibition of Constitutively Activated Phosphoinositide 3-Kinase/AKT Pathway Enhances Antitumor Activity of Chemotherapeutic Agents in Breast Cancer Susceptibility Gene 1-Defective Breast Cancer Cells [O] . Yong Weon Yi, Hyo Jin Kang, Hee Jeong Kim, -1

机译：抑制组成型活化的磷酸阳性3-激酶/ AKT途径增强了乳腺癌易感性基因1缺陷乳腺癌细胞中化学治疗剂的抗肿瘤活性
7. Combination of Quercetin and 2-Methoxyestradiol Enhances Inhibition of Human Prostate Cancer LNCaP and PC-3 Cells Xenograft Tumor Growth. [O] . Feiya Yang, Liming Song, Huiping Wang, 2015

机译：槲皮素和2-甲氧基雌二醇的组合增强了人前列腺癌LNCap和pC-3细胞异种移植肿瘤生长的抑制。

Enhanced inhibition of tumor growth using TRAIL-overexpressing adipose-derived stem cells in combination with the chemotherapeutic agent CPT-11 in castration-resistant prostate cancer

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