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Prescribing Patterns of Pain Medications in Unspecific Low Back Pain in Primary Care: A Retrospective Analysis

机译:在初级保健中规定止痛疼痛止痛药的止痛药模式:回顾性分析

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摘要

Acute low back pain (LBP) is one of the most prevalent diseases worldwide. Since there is evidence of excessive prescriptions of analgesics, i.e., opioids, the aim of this study was to describe the use of pain medications in patients with LBP in the Swiss primary care setting. A retrospective, observational study was performed using medical prescriptions of 180 general practitioners (GP) during years 2009–2020. Patterns of pain medications (nonsteroidal anti-inflammatory drugs (NSAIDs), paracetamol, and opioids) as well as co-medications were analyzed in patients with a LBP diagnosis. Univariable and multivariable regression analyses assessed GP and patient characteristics associated with the prescription of pain medication. Patients included were 10,331 (mean age 51.7 years, 51.2% female); 6449 (62.4%) received at least one pain medication and of these 86% receive NSAIDs and 22% opioids. GP characteristics (i.e., self-employment status) and patient characteristics (male gender and number of consultations) were associated with significantly higher odds of receiving any pain medication in multivariable analysis. 3719 patients (36%) received co-medications. Proton-pump-inhibitors and muscle relaxants were the most commonly used co-medications. In conclusion, two-thirds of LBP patients were treated with pain medications. Prescribing patterns were conservative, with little use of strong opioids and co-medications.
机译:急性低腰疼(LBP)是全球最普遍的疾病之一。由于存在过量镇痛药的证据,即阿片类药物,本研究的目的是描述瑞士初级护理环境中LBP患者患者疼痛药物的使用。在2009 - 2020年20日期,使用180名全科医生(GP)的医疗处方进行了回顾性的观察研究。患有LBP诊断的患者中分析了止痛药的模式(非甾体抗炎药(NSAIDs),扑热息痛和阿片类药物)以及共同药物。与止痛药与止痛药处方相关的GP和患者特征,不可变量和多变量的回归分析。患者包括10,331(平均51.7岁,女性51.2%); 6449(62.4%)收到至少一种止痛药,其中86%接受NSAIDs和22%的阿片类药物。 GP特征(即,自雇人士状态)和患者特征(男性性别和咨询人数)与在多变量分析中接受任何疼痛药物的几率明显较高。 3719名患者(36%)接受了共同药物。质子泵抑制剂和肌肉松弛剂是最常用的共同药物。总之,三分之二的LBP患者用止痛药治疗。规定模式是保守的,很少使用强甲型物质和共同药物。

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