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Statistics and Patterns of Occurrence of Simple Tandem Repeats in SARS-CoV-1 and SARS-CoV-2 Genomic Data

机译:SARS-COV-1和SARS-COV-2基因组数据中简单串联重复的统计和模式

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摘要

The data presented in this article is related to the research article entitled “Developing an ultra-efficient microsatellite discoverer to find structural differences between SARS-CoV-1 and Covid-19” [Naghibzadeh et al. 2020]. Simple tandem repeats (microsatellites, STR) are extracted and investigated across all viral families from four main viral realms. An ultra-efficient and reliable software, which is recently developed by the authors and published in the above-mentioned article, is used for extracting STRs. The analysis is done for k-mer tandem repeats where k varies from one to seven. In particular the frequency of trimer STRs is shown to be low in RNA viruses compared with DNA viruses. Special attention is paid to seven zoonotic viruses from family Coronaviridae which caused several severe human crises during last two decades including MERS, SARS 2003 and Covid-19.
机译:本文提出的数据与题为“开发超高效微卫星发现者的研究文章有关,以找到SARS-COV-1和Covid-19之间的结构差异[Nagibhzadeh等人。 2020]。在来自四个主要病毒领域的所有病毒族中提取和研究简单的串联重复(微卫星,str)。超高效可靠的软件,最近由作者开发并在上述文章中发布,用于提取strs。分析是针对K-MER串联重复的,其中K从一到七种。特别地,与DNA病毒相比,Trimer strs的频率显示在RNA病毒中是低的。特别注意来自家族冠状病毒的七种动物病毒,在过去二十年中导致了几个严重的人类危机,包括MERS,SARS 2003和Covid-19。

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