Effect of 19-Norandrostenololylaurate on Semen Characteristics of Colts

摘要

The long-term effects of the anabolic steroid 19-norandrostenololylaurate on semen characteristics of Finnhorse colts were studied in 3 experiments. Semen was collected initially at 24 months of age and then twice a year. In experiment I, 500 mg or 100 mg of steroid per animal was given every 3rd week from 12 or 16 months to 24 months of age. In colts treated with 500 mg of anabolic steroid every 3rd week, azoospermia was observed in 3 out of 5 colts in the first semen collections, immediately after the end of treatment. The other 2 colts had low sperm numbers and a high percentage of proximal droplets in relation to control animals. The 100 mg group was less affected by steroid treatment than the 500 mg group. The seminal changes were observed to be reversible. All of the colts had spermatozoa in their ejaculates 4 months after the end of treatment. Two years after cessation of treatment, sperm numbers in treated animals exceeded those in the control group.