LINGO-1 regulates Wnt5a signaling during neural stem and progenitor cell differentiation by modulating miR-15b-3p levels

摘要

Schematic illustration of sp-NSPC culture, differentiation, and experimental design. A sp-NSPCs, harvested from injured spinal cords, differentiated into neurons, astrocytes, and oligodendrocytes. B Transplantation of LINGO-1 shRNA-treated sp-NSPCs and timeline for motor function analysis