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Human umbilical cord mesenchymal stem cells deliver exogenous miR-26a-5p via exosomes to inhibit nucleus pulposus cell pyroptosis through METTL14/NLRP3

机译：人的脐带间充质干细胞通过外泌体递送外源miR-26a-5p以通过MetT114 / NLRP3抑制核髓细胞γ糊化症

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The online version contains supplementary material available at 10.1186/s10020-021-00355-7.

机译：在线版本包含10.1186 / S10020-021-00355-7可用的补充材料。

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期刊名称 Molecular Medicine
作者
Xiaoqiu Yuan; Tiefeng Li; Lei Shi; Jinhao Miao; Yongfei Guo; Yu Chen;
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作者单位

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年(卷),期 2021(-1),-1
年度 2021
页码 -1
总页数 16
原文格式 PDF
正文语种
中图分类分子生物学;细胞生物学;医学史;
关键词

机译：椎间盘退化;ñ;

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专利

1. Mesenchymal stem cells deliver exogenous miR‐21 via exosomes to inhibit nucleus pulposus cell apoptosis and reduce intervertebral disc degeneration [J] . Xiaofei Cheng, Guoying Zhang, Liang Zhang, Journal of cellular and molecular medicine. . 2018,第1期

机译：间充质干细胞通过外来渗透外源miR-21，以抑制核脉搏细胞凋亡并减少椎间盘变性
2. Exosomes derived from human umbilical cord mesenchymal stromal cells deliver exogenous miR-145-5p to inhibit pancreatic ductal adenocarcinoma progression [J] . Ding Yixuan, Cao Feng, Sun Haichen, Cancer letters . 2019,第期

机译：源自人脐部间充质基质细胞的外泌体可递送外源miR-145-5p以抑制胰腺导管腺癌进展
3. Human umbilical cord mesenchymal stromal cells exhibit immature nucleus pulposus cell phenotype in a laminin-rich pseudo-three-dimensional culture system [J] . Brian H Chon, Esther J Lee, Liufang Jing, Stem Cell Research & Therapy . 2013,第5期

机译：人脐带间充质基质细胞在富含层粘连蛋白的伪三维培养系统中表现出未成熟的髓核细胞表型
4. SCALABLE EXPANSION OF HUMAN UMBILICAL CORD MATRIX- AND ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM/STROMAL CELLS AND DERIVED EXOSOMES IN THE SINGLE-USE, VERTICAL-WHEEL BIOREACTOR SYSTEM USING A HUMAN PLATELET LYSATE CULTURE SUPPLEMENT [C] . Ana Fernandes-Platzgummer, Diogo de Sousa Pinto, Miguel de Almeida Fuzeta, Conference on advancing manufacture of cell and gene therapies . 2019

机译：单次使用垂直轮生物反应器系统中人类脐带基质和脂肪组织来源的间充质干细胞/基质细胞和衍生的外来体的可扩展性，使用人类血小板裂解液培养物
5. Effects of Design Factors and Microenvironment on Mesenchymal Stem Cells and Nucleus Pulposus Cells for Intervertebral Disc Tissue Engineering. [D] . Ouyang, Ann. 2017

机译：设计因素和微环境对间质干细胞和髓核细胞进行椎间盘组织工程的影响。
6. Mesenchymal stem cells deliver exogenous miR‐21 via exosomes to inhibit nucleus pulposus cell apoptosis and reduce intervertebral disc degeneration [O] . Xiaofei Cheng, Guoying Zhang, Liang Zhang, 2018

机译：间充质干细胞通过外泌体传递外源性miR-21以抑制髓核细胞凋亡并减少椎间盘退变
7. Effect of Conditioned Medium from Human Umbilical Cord-Derived Mesenchymal Stromal Cells on Rejuvenation of Nucleus Pulposus Derived Stem/Progenitor Cells from Degenerated Intervertebral Disc [O] . Xiaoli Zeng, Jinhua Lin, Hao Wu, 2020

机译：人脐带源性间充质细胞的条件培养基对退化椎间盘源性茎/祖细胞的恢复效应

Human umbilical cord mesenchymal stem cells deliver exogenous miR-26a-5p via exosomes to inhibit nucleus pulposus cell pyroptosis through METTL14/NLRP3

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