Luminescent property and application values of a new Cd(II) compound in tuberculosis treatment and clinical nursing

摘要

Through the reaction between HTrz and Cd(NO3)2 · 4H2O, a new Cd(II) compound of [Cd(Trz) 2] n (1, HTrz = 1,2,4-triazole) can be obtained, which has been studied with diffraction analysis by single crystal X-ray as well as powder X-ray diffraction. The structure of 1 can be stable up to 265°C, and the solid samples of 1 emit intense blue luminescence at room temperature. Along with the evaluation of tuberculosis treatment and clinical nursing, related mechanism was also studied here. Firstly, ELISA assay was conducted and the IL-10 and IL-18 released into the alveolar lavage fluid was determined. Apart from this, the real-time RT-PCR was used to reflect surviving gene’s relative expression of Mycobacterium tuberculosis after compound treatment.