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Data on biodistribution and dose calculation of 99mTechnetium -Dimercaptosuccinic acid in pediatric patients using a hybrid planar/single emission computed tomography method

机译:采用混合平面/单排放计算断层扫描方法对儿科患者99Mtechnetium-Dimercincinic酸的生物分布和剂量计算数据

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摘要

The Biodistribution and absorbed dose data from the administration of radiopharmaceuticals are necessary to analyze the risk-benefit of the procedure. It has particular significance in children, as their metabolism is very different from adults. 99mTc-DMSA scintigraphy is the golden standard imaging technique for the assessment of renal involvement in febrile urinary tract infection and renal sequels. However, 99mTc-DMSA biodistribution data for children are scarce and usually outdated which have been obtained by older methods. In this data article, we analysed the biodistribution of 99mTc-DMSA in 12 pediatric patients using planar/SPECT method. In addition, the radiation absorbed doses were calculated by MIRDOSE software.
机译:来自给药给药的生物分布和吸收剂量数据是分析程序的风险益处所必需的。它在儿童中具有特殊的重要意义,因为他们的新陈代谢与成年人截然不同。 99MTC-DMSA Scintigraphy是用于评估发热性尿路感染和肾续期肾脏参与的金标准成像技术。然而,99MTC-DMSA儿童生物分布数据稀缺,通常通过较旧方法获得的过时。在本数据文章中,我们在使用平面/ SPECT方法分析了12名儿科患者中99MTC-DMSA的生物分布。此外,通过髓软件计算辐射吸收剂量。

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