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The development of a novel autologous blood glue aiming to improve osseointegration in the bone-implant interface

机译:一种新型自体血液胶水旨在改善骨植入界面中的骨整合

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摘要

For cementless implants, stability is initially attained by an interference fit into the bone and osteo-integration may be encouraged by coating the implant with bioactive substances. Blood based autologous glue provides an easy, cost-effective way of obtaining high concentrations of growth factors for tissue healing and regeneration with the intention of spraying it onto the implant surface during surgery. The aim of this study was to incorporate nucleated cells from autologous bone marrow (BM) aspirate into gels made from the patient’s own blood, and to investigate the effects of incorporating three different concentrations of platelet rich plasma (PRP) on the proliferation and viability of the cells in the gel.
机译:对于无固态植入物,最初通过磨合骨灰拟合而最初获得稳定性,并且可以通过用生物活性物质涂覆植入物来鼓励骨液集成。血基自体胶水提供了一种容易,成本效益的方法来获得组织愈合和再生的高浓度的生长因子,其意图在手术期间将其喷洒到植入物表面上。本研究的目的是将核心细胞纳入自体骨髓(BM)中吸出从患者自己的血液制成的凝胶中,并研究掺入三种不同浓度的血小板富血浆(PRP)对增殖和活力的影响凝胶中的细胞。

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