Stroke-like Episodes in m.3243A≥G Carriers Need to Be Monitored by MRI Starting with the Onset of Clinical Manifestations

摘要

With interest, we read the article by Bhatia et al1 about a retrospective study of 8 patients with genetically confirmed mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS). It was found that among 31 imaging studies, performed between 2006 and 2018, forty-one lesions were “new” in 17 studies.1 It was concluded that cortical lesions most commonly affect the primary visual, the primary somatosensory, and the primary auditory cortices.1 The study has a number of limitations and shortcomings.