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Epileptic seizure onset detection prior to clinical manifestation

机译:临床表现之前发现癫痫发作

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摘要

In this paper, we present the design of an epilepticseizure detector. This circuit is part of an implantable device used to continuously record intracerebral electroencephalographic signals through subdural and depth electrodes. The implemented seizure detector is based on a detection algorithm validated in Matlab tools and the circuits were implemented using CMOS 0.18-µm process. The proposed system was tested using intracerebral EEG recordings from two patients with drug-resistant epilepsy. Four seizures were assessed by the proposed CMOS building blocks and the required delays to detect these seizures were 3, 8, 11, and 11 sec, respectively after electric onset. The simulated total power consumption of the detector was 6.71 µW. Together, these preliminary results indicate the possibility of building implantable ultra-low power seizure-detection devices.
机译:在本文中,我们介绍了癫痫发作检测器的设计。该电路是可植入设备的一部分,用于通过硬膜下和深度电极连续记录脑电图。实施的癫痫发作检测器基于在Matlab工具中验证过的检测算法,电路采用CMOS 0.18 µm工艺实现。使用来自两名耐药性癫痫患者的脑内脑电图记录对所提出的系统进行了测试。通过建议的CMOS构造块评估了4次癫痫发作,检测到这些癫痫发作所需的延迟时间分别为电发作后3、8、11和11秒。检测器的模拟总功耗为6.71 µW。总之,这些初步结果表明,有可能制造可植入的超低功率癫痫发作检测设备。

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