The role of antibiotic-loaded bone cement in complicated knee arthroplasty: relevance of gentamicin allergy and benefit from revision surgery — a case control follow-up study and algorithmic approach

摘要

Traditional orthopaedic work-up of common problem elicitors. The initial work-up for complicated TKAs is carried out by the treating orthopaedic surgeon and commences with detailed history taking and a through clinical examination. Once systemic and extra-articular etiologies are ruled out, specific TKA-related problems are addressed. In cases of inconclusive work-up, rare conditions, such as allergic or adverse reactions, should be considered as diagnoses of exclusion (R/O, rule out; CT, computed tomography; CRP, C-reactive protein; WBC, white blood cell count; ESR, erythrocyte sedimentation rate; PCT, procalcitonin; IL-6 , interleukin-6, SPECT, single photon emission computed tomography; PET, positron emission tomography; MRI, magnetic resonance imaging)