Advances in research on the interaction between inflammationand cancer

摘要

Inflammation is the body's response to cell damage. Cancer is a generalterm that describes all malignant tumours. There are no confirmed dataon cancer-related inflammation, but some research suggests that up to50% of cancers may be linked to inflammation, which has led to theconcept of ‘cancer-associated inflammation’. Although some cancerpatients do not appear to have a chronic inflammatory background,there might be inflammatory cell infiltration in their cancer tissues.The continuation of the inflammatory response plays an important rolein the initiation, promotion, malignant transformation, invasion andmetastasis of cancer. Anti-inflammatory therapy has been shown to havesome effects on the prevention and treatment of cancer, which supportsa pathogenic relationship between inflammation and cancer. This reviewdescribes the interaction between inflammation and tumour developmentand the main mechanism of regulation of the inflammatory responseduring tumour development.