Ileocecal junction perforation by colonic T-cell lymphoma in a patient withprimary Sjögren’s syndrome

摘要

Primary Sjögren’s syndrome (pSS) is associated with an increased risk of lymphoma,especially non-Hodgkin’s lymphoma. The rarest pathological subtype is T-cell lymphoma. Weherein report a case of a 52-year-old man with a 17-year history of pSS who was admittedto our hospital with chronic epigastric pain and a positive fecal occult blood test.Colonoscopy revealed multiple colonic ulcers, and histological and immunological studiesdemonstrated the T-cell origin of this lymphoma. However, the patient rejected alltreatments. He developed recurrent intestinal obstruction and infection for 3 years untilan intestinal perforation occurred. The right half of the colon was resected and colostomywas performed. However, the patient died of an intestinal fistula and intraperitonealinfection 40 days postoperatively. This case highlights the rarity of the correlationbetween T-cell lymphoma and pSS.