首页> 美国卫生研究院文献>The International Journal of Angiology : Official Publication of the International College of Angiology Inc >Carotid Body Baroreceptor Preservation and Control of Arterial Pressure in Eversion Carotid Endarterectomy
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Carotid Body Baroreceptor Preservation and Control of Arterial Pressure in Eversion Carotid Endarterectomy

机译:颈动脉体内丧失运动员保存和控制转化颈动脉压力下颌切除术

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摘要

The technique of the eversion carotid endarterectomy (ECEA), as an alternative to the conventional endarterectomy with primary or patch angioplasty, is an established technique for managing internal carotid artery stenoses and recently its application has been upgraded through the European Society for Vascular Surgery guidelines (Recommendation 55: Class 1, Level A). However, the typical eversion method has been associated with postoperative hypertension due to loss of the baroreceptor reflex; the standard oblique transection at the bulb performed in the eversion endarterectomy interrupts either the baroreceptor sensoring tissue, which is mostly located in the adventitia at the medial portion of the proximal internal carotid artery, or even the proper Hering nerve, a branch of the glossopharyngeal nerve. These actions deregulate the natural negative feedback of the carotid baroreceptor. Guided by the anatomical location of the baroreceptor sensor we have elaborated a slight modification of the classical ECEA to maintain as much as possible of the viable carotid baroreceptor sensoring surface. By extending the oblique incision distal to the carotid bifurcation in the medial part of the internal carotid artery stem, an eyebrow-like part of the proximal internal carotid artery is maintained and the axis from the sensoring tissue to the nerve of Hering is protected and following the endarterectomy, postoperative arterial blood pressure levels are lower than in the classical ECEA due to the maintenance of the efficiency of the baroreceptor reflex. During the period from September 2016 to November 2018, carotid endarterectomy was performed in 57 patients. Twenty-eight of them underwent the typical ECEA and 29 patients had the modified eyebrow eversion carotid endarterectomy (me-ECEA). The changes of blood pressure baseline during the postoperative course in ECEA and me-ECEA group were analyzed and compared. Postoperative hypertension was defined as an elevation of systolic blood pressure (SBP) greater than 140 mm Hg. Patients who underwent typical ECEA had significantly higher postoperative blood pressure values compared with those who underwent me-ECEA. Actually, the mean postoperative SBP was 172.67 ± 24.59 mm Hg in the typical ECEA group compared with 160.86 ± 12.83 mm Hg in the me-ECEA group (p = 0.023). The mean diastolic blood pressure in the ECEA group was 65.42 ± 11.39 mm Hg compared with 58.06 ± 9.06 mm Hg in the me-ECEA group (p = 0.009). Our proposed me-ECEA technique seems to be related to lower rates of postoperative hypertension compared with the typical ECEA, probably due to the sparing of the main mass of the baroreceptor apparatus; this improved modification (me-ECEA) of the typical eversion procedure could represent an alternative ECEA technique with its inherent advantages.
机译:在外翻颈动脉内膜切除术(ECEA)的技术中,作为替代与伯或血管补片的常规动脉内膜切除术,是用于管理颈内动脉狭窄和最近其应用已通过欧洲血管外科学会准则(升级的成熟技术建议55:第1类,A级)。然而,典型的外翻方法已经与术后高血压有关由于压力感受器反射损失;在外翻内膜切除术中断任一压力感受器感测的组织进行的灯泡,其大多位于外膜在近端颈内动脉的中间部分,或甚至适当的赫林神经,舌咽神经的分支的标准倾斜横断。这些行动放开颈动脉压力感受器的天然负反馈。由压力感受器的解剖位置引导传感器我们已经阐述了经典ECEA的略微修改以保持尽可能活颈动脉压力感受器感测的表面的。通过在颈内动脉干的内侧部分的倾斜切口远侧延伸至所述颈动脉分叉,眉毛状近侧颈内动脉的部分被保持,并从感测的组织赫林的神经轴被保护并且以下动脉内膜切除术,术后动脉血压水平由于维持压力感受器反射的效率比在古典ECEA低。在从2016年9月至2018年11月期间,在57例患者进行颈动脉内膜切除。二十八人经历了典型的ECEA和29例有修饰眉毛外翻动脉内膜切除术(ME-ECEA)。血压基线的ECEA和我-ECEA组术后过程中的变化进行了分析和比较。术后高血压被定义为收缩压(SBP)大于140毫米汞柱的正视图。与那些谁接受我,ECEA相比,谁接受典型ECEA患者有显著较高的术后血压值。实际上,术后平均收缩压为172.67±24.59毫米汞柱典型ECEA组与160.86±12.83毫米汞柱ME-ECEA组(比较P.= 0.023)。该ECEA组的平均舒张压65.42±11.39毫米汞柱58.06±9.06毫米汞柱ME-ECEA组(比较P.= 0.009)。我们提出的我,ECEA技术似乎与以降低术后高血压率与典型ECEA,可能是由于压力感受器装置的主要质量的节约相比;典型的外翻过程的这种改进的变形例(ME-ECEA)可以表示与它的固有的优点的替代ECEA技术。

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