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Piecewise quadratic growth during the 2019 novel coronavirus epidemic

机译:2019年新型冠状病毒流行病中分段二次生长

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摘要

The temporal growth in the number of deaths in the COVID-19 epidemic is subexponential. Here we show that a piecewise quadratic law provides an excellent fit during the thirty days after the first three fatalities on January 20 and later since the end of March 2020. There is also a brief intermediate period of exponential growth. During the second quadratic growth phase, the characteristic time of the growth is about eight times shorter than in the beginning, which can be understood as the occurrence of separate hotspots. Quadratic behavior can be motivated by peripheral growth when further spreading occurs only on the outskirts of an infected region. We also study numerical solutions of a simple epidemic model, where the spatial extend of the system is taken into account. To model the delayed onset outside China together with the early one in China within a single model with minimal assumptions, we adopt an initial condition of several hotspots, of which one reaches saturation much earlier than the others. At each site, quadratic growth commences when the local number of infections has reached a certain saturation level. The total number of deaths does then indeed follow a piecewise quadratic behavior.
机译:Covid-19流行病中死亡人数的时间生长是子期势。在这里,我们表明,分段二次法律在自2020年3月底以来的前三个死亡率之后的三十天内提供了极好的适合。还有一个简短的中间期限增长。在第二二次生长阶段期间,增长的特征时间比开始短八倍,这可以被理解为单独热点的发生。当仅在感染区域的郊区发生进一步展开时,可以通过外围增长激励二次行为。我们还研究了一个简单的疫情模型的数值解,其中考虑了系统的空间延伸。为了模拟中国以外的延迟发作以及中国的早期,在一个模型中的一个模型中,具有最小的假设,我们采用了几种热点的初始条件,其中一个热点比其他热点更早地达到饱和度。在每个网站时,当局部感染达到某种饱和度时,二次生长开始。然后确实遵循分段二次行为的总死亡人数。

著录项

  • 期刊名称 Infectious Disease Modelling
  • 作者

    Axel Brandenburg;

  • 作者单位
  • 年(卷),期 2020(-1),-1
  • 年度 2020
  • 页码 -1
  • 总页数 10
  • 原文格式 PDF
  • 正文语种
  • 中图分类 病毒传染病;
  • 关键词

    机译:Covid-19;冠状病毒;流行病;SIR模型;反应 - 扩散方程;

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